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NEB reseller listings, unsupported aliases and discontinued products were excluded." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-paci-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PacI restriction enzymes", "Standard formulations" ], "productCount": 2, "companies": [ "New England Biolabs", "Thermo Fisher Scientific" ], "nonNebProducts": 1, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-paci-restriction-enzymes-standard-formulations", "status": "supported-candidates", "queries": [ "PacI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [ "https://www.thermofisher.com/order/catalog/product/ER2201" ], "reason": "Manufacturer catalogs contain exact-name product listings. Recognition/cleavage behavior and experimental conditions still require comparison. 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No independently verified non-NEB direct product page established the same engineered enzyme/function constraints; similarly named or recognition-site-only products were not forced into this category." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-pcii-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PciI restriction enzymes", "Standard formulations" ], "productCount": 2, "companies": [ "New England Biolabs", "SibEnzyme" ], "nonNebProducts": 1, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-pcii-restriction-enzymes-standard-formulations", "status": "supported-candidates", "queries": [ "PciI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [ "https://sibenzyme.com/product/pci-i/" ], "reason": "Manufacturer catalogs contain exact-name product listings. 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NEB reseller listings, unsupported aliases and discontinued products were excluded." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-pi-scei-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PI-SceI restriction enzymes", "Standard formulations" ], "productCount": 1, "companies": [ "New England Biolabs" ], "nonNebProducts": 0, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-pi-scei-restriction-enzymes-standard-formulations", "status": "no-supported-match", "queries": [ "\"PI-SceI\" restriction enzyme manufacturer -site:neb.com -site:neb-online.de -site:neb-online.fr" ], "sourceUrls": [], "reason": "Exact-name manufacturer searches and manufacturer catalog checks did not establish an available non-NEB product with an official direct product page and sufficiently supported matching identity. 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Candidate status does not guarantee interchangeability." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-pluti-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PluTI restriction enzymes", "Standard formulations" ], "productCount": 2, "companies": [ "New England Biolabs", "Nippon Genetics Europe" ], "nonNebProducts": 1, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-pluti-restriction-enzymes-standard-formulations", "status": "supported-candidates", "queries": [ "\"PluTI\" restriction enzyme manufacturer -site:neb.com -site:neb-online.de -site:neb-online.fr" ], "sourceUrls": [ "https://www.nippongenetics.eu/produkte/restriktionsenzyme/plut-i/" ], "reason": "Official manufacturer product page supports the named enzyme or expressly identified matching-cleavage isoschizomer. Candidate status does not guarantee interchangeability." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-pmei-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PmeI restriction enzymes", "Standard formulations" ], "productCount": 1, "companies": [ "New England Biolabs" ], "nonNebProducts": 0, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-pmei-restriction-enzymes-standard-formulations", "status": "no-supported-match", "queries": [ "PmeI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [], "reason": "No independent exact-formulation candidate was established in the examined manufacturer catalogs." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-pmli-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PmlI restriction enzymes", "Standard formulations" ], "productCount": 1, "companies": [ "New England Biolabs" ], "nonNebProducts": 0, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-pmli-restriction-enzymes-standard-formulations", "status": "no-supported-match", "queries": [ "PmlI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [], "reason": "No independent exact-formulation candidate was established in the examined manufacturer catalogs." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-ppumi-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PpuMI restriction enzymes", "Standard formulations" ], "productCount": 1, "companies": [ "New England Biolabs" ], "nonNebProducts": 0, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-ppumi-restriction-enzymes-standard-formulations", "status": "no-supported-match", "queries": [ "PpuMI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [], "reason": "No independent exact-formulation candidate was established in the examined manufacturer catalogs." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-pshai-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PshAI restriction enzymes", "Standard formulations" ], "productCount": 1, "companies": [ "New England Biolabs" ], "nonNebProducts": 0, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-pshai-restriction-enzymes-standard-formulations", "status": "no-supported-match", "queries": [ "PshAI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [], "reason": "No independent exact-formulation candidate was established in the examined manufacturer catalogs." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-psii-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PsiI restriction enzymes", "Standard formulations" ], "productCount": 2, "companies": [ "New England Biolabs", "SibEnzyme" ], "nonNebProducts": 1, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-psii-restriction-enzymes-standard-formulations", "status": "supported-candidates", "queries": [ "PsiI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [ "https://sibenzyme.com/product/psi-i/" ], "reason": "Manufacturer catalogs contain exact-name product listings. Recognition/cleavage behavior and experimental conditions still require comparison. Related enzyme names alone do not create exact membership." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-pspgi-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PspGI restriction enzymes", "Standard formulations" ], "productCount": 3, "companies": [ "BestEnzymes", "New England Biolabs", "Nippon Genetics Europe" ], "nonNebProducts": 2, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-pspgi-restriction-enzymes-standard-formulations", "status": "supported-candidates", "queries": [ "\"PspGI\" restriction enzyme manufacturer -site:neb.com -site:neb-online.de -site:neb-online.fr" ], "sourceUrls": [ "https://www.nippongenetics.eu/produkte/restriktionsenzyme/pspg-i/", "https://en.best-enzymes.com/cms/LightNingTMxianzhixingxianzhimei/201.html" ], "reason": "Official manufacturer product page supports the named enzyme or expressly identified matching-cleavage isoschizomer. Candidate status does not guarantee interchangeability." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-pspomi-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PspOMI restriction enzymes", "Standard formulations" ], "productCount": 2, "companies": [ "New England Biolabs", "SibEnzyme" ], "nonNebProducts": 1, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-pspomi-restriction-enzymes-standard-formulations", "status": "supported-candidates", "queries": [ "PspOMI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [ "https://sibenzyme.com/product/pspom-i/" ], "reason": "Manufacturer catalogs contain exact-name product listings. Recognition/cleavage behavior and experimental conditions still require comparison. Related enzyme names alone do not create exact membership." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-pspxi-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PspXI restriction enzymes", "Standard formulations" ], "productCount": 2, "companies": [ "New England Biolabs", "SibEnzyme" ], "nonNebProducts": 1, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-pspxi-restriction-enzymes-standard-formulations", "status": "supported-candidates", "queries": [ "PspXI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [ "https://sibenzyme.com/product/pspx-i/" ], "reason": "Manufacturer catalogs contain exact-name product listings. Recognition/cleavage behavior and experimental conditions still require comparison. 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Standard enzymes and FastDigest/LightNing marketing were not counted as HF equivalents." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-psti-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "PstI restriction enzymes", "Standard formulations" ], "productCount": 5, "companies": [ "Jena Bioscience", "New England Biolabs", "SibEnzyme", "Thermo Fisher Scientific" ], "nonNebProducts": 3, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-psti-restriction-enzymes-standard-formulations", "status": "supported-candidates", "queries": [ "PstI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [ "https://www.thermofisher.com/order/catalog/product/ER0611", "https://sibenzyme.com/product/pst-i/", "https://www.jenabioscience.com/molecular-biology/enzymes-protein-markers/restriction-enzymes/p-enzymes/en-127-psti" ], "reason": "Manufacturer catalogs contain exact-name product listings. 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Standard enzymes and FastDigest/LightNing marketing were not counted as HF equivalents." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-swai-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "SwaI restriction enzymes", "Standard formulations" ], "productCount": 1, "companies": [ "New England Biolabs" ], "nonNebProducts": 0, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-swai-restriction-enzymes-standard-formulations", "status": "no-supported-match", "queries": [ "SwaI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [], "reason": "No independent exact-formulation candidate was established in the examined manufacturer catalogs." } ], "correctedProducts": [] }, { "categoryId": "dna-genome-engineering-restriction-digestion-taqi-restriction-enzymes-standard-formulations", "path": [ "DNA & genome engineering", "Restriction digestion", "TaqI restriction enzymes", "Standard formulations" ], "productCount": 4, "companies": [ "Jena Bioscience", "New England Biolabs", "SibEnzyme", "Thermo Fisher Scientific" ], "nonNebProducts": 3, "audit": [ { "categoryId": "dna-genome-engineering-restriction-digestion-taqi-restriction-enzymes-standard-formulations", "status": "supported-candidates", "queries": [ "TaqI restriction enzymes exact identity in manufacturer conventional, rapid-digest and product catalogs" ], "sourceUrls": [ "https://www.thermofisher.com/order/catalog/product/ER0671", "https://sibenzyme.com/product/taq-i/", "https://www.jenabioscience.com/molecular-biology/enzymes-protein-markers/restriction-enzymes/t-enzymes/en-142-taqi" ], "reason": "Manufacturer catalogs contain exact-name product listings. 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Recognition/cleavage behavior and experimental conditions still require comparison. 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Recognition/cleavage behavior and experimental conditions still require comparison. Related enzyme names alone do not create exact membership." } ], "correctedProducts": [] }, { "categoryId": "nucleic-acid-purification-dna-purification-agarose-digestion", "path": [ "Nucleic acid purification", "DNA purification", "Agarose digestion" ], "productCount": 2, "companies": [ "New England Biolabs", "Thermo Fisher Scientific" ], "nonNebProducts": 1, "audit": [ { "categoryId": "nucleic-acid-purification-dna-purification-agarose-digestion", "status": "supported-candidates", "queries": [ "Agarose digestion official manufacturer catalog" ], "sourceUrls": [ "https://www.thermofisher.com/order/catalog/product/es/en/EO0461" ], "reason": "Official product metadata found. Category association does not establish experimental interchangeability." } ], "correctedProducts": [] }, { "categoryId": "laboratory-essentials-labware-tubes-accessories", "path": [ "Laboratory essentials", "Labware", "Tubes & accessories" ], "productCount": 0, "companies": [], "nonNebProducts": 0, "audit": [ { "categoryId": "laboratory-essentials-labware-tubes-accessories", "status": "supported-candidates", "queries": [ "Tubes & accessories reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr", "2 ml microcentrifuge tubes Eppendorf Safe Lock" ], "sourceUrls": [ "https://www.eppendorf.com/us-en/Products/Lab-Consumables/Lab-Tubes/Eppi-Eppendorf-Safe-Lock-Tubes-p-PF-8863" ], "reason": "Mixed labware types require separate final categories." } ], "correctedProducts": [ { "product": "cryogenic-cold-storage-box-t1041", "from": "laboratory-essentials-labware-tubes-accessories", "to": "laboratory-essentials-labware-tubes-accessories-81-position-fiberboard-freezer-boxes", "reason": "Officially an 81-position fiberboard box for 1 to 2 mL tubes, not tubes themselves. 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Color and purity grade have not been established for this exact catalog record; do not infer these from the product family." }, { "product": "neb-tube-opener-c1008", "from": "laboratory-essentials-labware-tubes-accessories", "to": "laboratory-essentials-labware-tubes-accessories-microcentrifuge-tube-openers", "reason": "Official page identifies a tool for opening snap and screw caps, not consumable tubes." }, { "product": "eppendorf-eppendorf-safe-lock-tubes-2-0-ml", "from": "laboratory-essentials-labware-tubes-accessories", "to": "laboratory-essentials-labware-tubes-accessories-2-ml-microcentrifuge-tubes-color-and-purity-grade-unspecified", "reason": "Catalog identifies 2 mL microcentrifuge tubes. Low-binding surface, cap closure, purity grade and rotor compatibility still require product-specific review. Color and purity grade have not been established for this exact catalog record; do not infer these from the product family." } ] }, { "categoryId": "protein-glycobiology-affinity-purification-streptavidin-beads", "path": [ "Protein & glycobiology", "Affinity purification", "Streptavidin beads" ], "productCount": 4, "companies": [ "Advanced BioChemicals", "BEAVER", "New England Biolabs" ], "nonNebProducts": 2, "audit": [ { "categoryId": "protein-glycobiology-affinity-purification-streptavidin-beads", "status": "supported-candidates", "queries": [ "Streptavidin beads reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr" ], "sourceUrls": [ "https://en.beaverbio.com/products/view/1124.html", "https://advancedbiochemicals.com/product/streptavidin-magnetic-beads/" ], "reason": "Manufacturer documents support candidate function; experimental interchangeability is not established." } ], "correctedProducts": [] }, { "categoryId": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-buffer-b1", "path": [ "Laboratory essentials", "Buffers & solutions", "Reaction buffers", "Purification buffers", "Monarch Buffer B1" ], "productCount": 0, "companies": [], "nonNebProducts": 0, "audit": [ { "categoryId": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-buffer-b1", "status": "proprietary-category", "queries": [ "Monarch Buffer B1 reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr" ], "sourceUrls": [ "https://bionordika.no/Files/Files/Norway/FilesSuppliers/NEB/manualT1110.pdf", "https://kemns.com/article/%EB%B8%8C%EB%9E%9C%EB%93%9C%EB%B3%84-%EC%A0%9C%ED%92%88-%EB%A6%AC%EC%8A%A4%ED%8A%B8/1/290/", "https://www.euroclonegroup.it/documents/documents/NEB-Monarch-Brochure-DNA-2503.pdf", "https://labettor.com/uploads/products/protocols/2123.pdf", "https://www.bhu.ac.in/Images/files/Zelle%20Price%20List%202024-26.pdf", "https://bionordika.fi/topics/molecular-biology/nucleic-acid-quantitation?Supplier=New+England+Biolabs", "https://adorisgroup.com/product/neb/monarch-buffer-wz-1", "https://www.vwr.com/pr/en/product/BP0000617003/monarch-buffer-b2" ], "reason": "Brand-specific formulation or strain. 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Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." } ] }, { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-loading-formulation-unspecified", "path": [ "Analysis & standards", "Molecular weight standards", "DNA ladders", "50 bp DNA ladders", "Loading formulation unspecified" ], "productCount": 0, "companies": [], "nonNebProducts": 0, "audit": [ { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-loading-formulation-unspecified", "status": "supported-candidates", "queries": [ "Molecular weight standards DNA ladders 50 bp DNA ladders reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr", "50 bp DNA ladder Takara 3420A", "50 bp DNA ladder site:intronbio.com OR site:takara-bio.com", "\"50 bp DNA Ladder\" \"Thermo\" \"SM0371\"" ], "sourceUrls": [ "https://www.thermofisher.com/order/catalog/product/SM0371" ], "reason": "Manufacturer documents support candidate function; experimental interchangeability is not established." } ], "correctedProducts": [ { "product": "50-bp-dna-ladder-n3236", "from": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 50-1350 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "thermo-scientific-generuler-50-bp-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 50-1000 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." } ] }, { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "path": [ "Analysis & standards", "Molecular weight standards", "DNA ladders", "1 kb DNA ladders", "Standard-range 1 kb ladders", "Loading formulation unspecified" ], "productCount": 0, "companies": [], "nonNebProducts": 0, "audit": [ { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "status": "supported-candidates", "queries": [ "DNA ladders 1 kb DNA ladders Standard-range 1 kb ladders reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr", "1 kb DNA ladder site:promega.com" ], "sourceUrls": [ "https://www.promega.com/products/cloning-and-dna-markers/dna-ladder-rna-ladder/1kb-dna-ladder/" ], "reason": "Manufacturer documents support candidate function; experimental interchangeability is not established." } ], "correctedProducts": [ { "product": "dna-ladder-1-kb-n3232", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 500 bp to 10 kb. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "tridye-1-kb-dna-ladder-n3272", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-ready-to-load-ladders", "reason": "Official manufacturer product page confirms premixed ready-to-load format. Reported size coverage: 500 bp to 10 kb. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "thermo-scientific-generuler-1-kb-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 250 bp to 10 kb. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "zymo-research-zr-1-kb-dna-marker", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer variant table distinguishes concentrated 500 bp to 10 kb; M5003 variants only from separately listed ready-to-load SKU. Official gel image documents the band range. Requires root removal of ready-to-load variant pack from this family record before candidate status." }, { "product": "promega-1kb-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official page component table lists DNA ladder and 6 X Blue/Orange dye as separate items; fragment range 250-10000 bp. Preserve increment class and compare exact bands." } ] }, { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "path": [ "Analysis & standards", "Molecular weight standards", "DNA ladders", "100 bp DNA ladders", "Standard-range 100 bp ladders", "Loading formulation unspecified" ], "productCount": 0, "companies": [], "nonNebProducts": 0, "audit": [ { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "status": "supported-candidates", "queries": [ "DNA ladders 100 bp DNA ladders Standard-range 100 bp ladders reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr", "100 bp DNA ladder site:promega.com" ], "sourceUrls": [ "https://worldwide.promega.com/products/cloning-and-dna-markers/dna-ladder-rna-ladder/100bp-dna-ladder/" ], "reason": "Manufacturer documents support candidate function; experimental interchangeability is not established." } ], "correctedProducts": [ { "product": "dna-ladder-100-bp-n3231", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 100-1517 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "thermo-scientific-generuler-100-bp-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 100-1000 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "invitrogen-100-bp-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 100-2000 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "zymo-research-zr-100-bp-dna-marker", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer variant table distinguishes concentrated 100-1500 bp; M5002 variants only from separately listed ready-to-load SKU. Official gel image documents the band range. Requires root removal of ready-to-load variant pack from this family record before candidate status." }, { "product": "promega-100bp-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official page component table lists DNA ladder and 6 X Blue/Orange dye as separate items; fragment range 100-1500 bp. Preserve increment class and compare exact bands." }, { "product": "tridye-100-bp-dna-ladder-n3271", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ready-to-load-ladders", "reason": "Official product page confirms 100-1517 bp and premixed ready-to-load format with 3 tracking dyes." } ] }, { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "path": [ "Analysis & standards", "Molecular weight standards", "DNA ladders", "DNA ladders with unspecified increments", "Loading formulation unspecified" ], "productCount": 0, "companies": [], "nonNebProducts": 0, "audit": [ { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "status": "supported-candidates", "queries": [ "Molecular weight standards DNA ladders DNA ladders with unspecified increments reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr", "supercoiled DNA ladder site:thermofisher.com", "\"Supercoiled DNA Ladder\" \"15622012\" \"thermofisher.com/order\"" ], "sourceUrls": [ "https://assets.thermofisher.com/TFS-Assets/LSG/manuals/15622012.pdf" ], "reason": "Unspecified marker category mixes fast, supercoiled and ultra-low-range standards." } ], "correctedProducts": [ { "product": "fast-dna-ladder-n3238", "from": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-mixed-increment-dna-ladders-50-bp-to-10-kb-fast-electrophoresis-ladders-ready-to-load-ladders", "reason": "Official manufacturer product page confirms premixed ready-to-load format. Reported size coverage: 50 bp to 10 kb; 11 bands for fast electrophoresis. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "tridye-ultra-low-range-dna-ladder-n0558", "from": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-ready-to-load-ladders", "reason": "Official manufacturer product page confirms premixed ready-to-load format. Reported size coverage: 10-700 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "lambda-dna-mono-cut-mix-n3019", "from": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-lambda-single-cut-mixture-markers-1-5-48-5-kb-markers-ladders-requiring-loading-dye", "reason": "Official product table documents 10 fragments from 1503 to 48502 bp and separate loading dye; not a conventional evenly incremented ladder." }, { "product": "supercoiled-extend-dna-ladder-n0494", "from": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-supercoiled-dna-ladders-2-15-kb-supercoiled-plasmid-ladders-ladders-requiring-loading-dye", "reason": "Official product lists nine supercoiled plasmids, 2-15 kb, and separate loading dye. Supercoiled markers must not be matched to linear DNA ladders." }, { "product": "invitrogen-supercoiled-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-supercoiled-dna-ladders-2-16-kb-supercoiled-plasmid-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer MAN0001284 documents 11 plasmids, 2-16 kb, in Tris/EDTA buffer. Current official product URL returns a generic product-code page without descriptive content, so availability/direct-page confirmation remains unresolved." } ] }, { "categoryId": "analysis-standards-reference-nucleic-acids-dna-templates-lambda-dna", "path": [ "Analysis & standards", "Reference nucleic acids", "DNA templates", "Lambda DNA" ], "productCount": 2, "companies": [ "New England Biolabs", "Thermo Fisher Scientific" ], "nonNebProducts": 1, "audit": [ { "categoryId": "analysis-standards-reference-nucleic-acids-dna-templates-lambda-dna", "status": "supported-candidates", "queries": [ "Lambda DNA reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr" ], "sourceUrls": [ "https://tools.thermofisher.com/content/sfs/manuals/MAN0012976_Lambda_DNA_UG.pdf" ], "reason": "Manufacturer documents support candidate function; experimental interchangeability is not established." } ], "correctedProducts": [] }, { "categoryId": "analysis-standards-reference-nucleic-acids-dna-templates-lambda-dna-n6-methyladenine-free", "path": [ "Analysis & standards", "Reference nucleic acids", "DNA templates", "Lambda DNA (N6-methyladenine-free)" ], "productCount": 3, "companies": [ "New England Biolabs", "Promega", "Thermo Fisher Scientific" ], "nonNebProducts": 2, "audit": [ { "categoryId": "analysis-standards-reference-nucleic-acids-dna-templates-lambda-dna-n6-methyladenine-free", "status": "supported-candidates", "queries": [ "Lambda DNA (N6-methyladenine-free) reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr", "unmethylated lambda DNA site:promega.com OR site:thermofisher.com" ], "sourceUrls": [ "https://france.promega.com/en/products/biochemicals-and-labware/nucleic-acids/unmethylated-lambda-dna/", "https://www.thermofisher.com/order/catalog/product/SD0021" ], "reason": "Manufacturer documents support candidate function; experimental interchangeability is not established." } ], "correctedProducts": [] }, { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "path": [ "Analysis & standards", "Molecular weight standards", "DNA ladders", "Restriction digest DNA markers", "Loading formulation unspecified" ], "productCount": 0, "companies": [], "nonNebProducts": 0, "audit": [ { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "status": "supported-candidates", "queries": [ "Molecular weight standards DNA ladders Restriction digest DNA markers reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr", "lambda HindIII DNA marker site:promega.com" ], "sourceUrls": [ "https://www.promega.com/products/cloning-and-dna-markers/dna-ladder-rna-ladder/lambda-dna-hindiii-markers/" ], "reason": "Manufacturer documents support candidate function; experimental interchangeability is not established." } ], "correctedProducts": [ { "product": "lambda-dna-hindiii-digest-n3012", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-lambda-hindiii-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer describes eight lambda HindIII fragments, 125-23130 bp, with separate loading dye. Distinguish this band pattern from pBR322 and phiX174 digests." }, { "product": "lambda-hind-iii-digest-n3012", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-lambda-hindiii-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer describes eight lambda HindIII fragments, 125-23130 bp, with separate loading dye. Distinguish this band pattern from pBR322 and phiX174 digests." }, { "product": "promega-lambda-dna-hindiii-markers", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-lambda-hindiii-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer describes eight lambda HindIII fragments, 125-23130 bp, with separate loading dye. Distinguish this band pattern from pBR322 and phiX174 digests." }, { "product": "pbr322-bstn-i-digest-n3031", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-pbr322-bstni-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer confirms named digest, 13-1857 bp range, and separate loading dye. Digest identity determines fragment pattern." }, { "product": "pbr322-msp-i-digest-n3032", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-pbr322-mspi-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer confirms named digest, 9-622 bp range, and separate loading dye. Digest identity determines fragment pattern." }, { "product": "phi-x-174-hae-iii-digest-n3026", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-phix174-haeiii-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer confirms named digest, 72-1353 bp range, and separate loading dye. Digest identity determines fragment pattern." } ] }, { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-loading-formulation-unspecified", "path": [ "Analysis & standards", "Molecular weight standards", "DNA ladders", "Pulsed-field DNA ladders", "Loading formulation unspecified" ], "productCount": 0, "companies": [], "nonNebProducts": 0, "audit": [ { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-loading-formulation-unspecified", "status": "no-supported-match", "queries": [ "Molecular weight standards DNA ladders Pulsed-field DNA ladders reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr", "\"pulsed field\" \"DNA ladder\" site:sigmaaldrich.com", "\"lambda\" \"PFG\" \"marker\" manufacturer -site:neb.com -site:neb.cn -site:fishersci.com", "lambda ladder PFG 1703635 Bio Rad", "lambda ladder PFG marker site:bio-rad.com", "site:bio-rad.com \"CHEF DNA\" \"Lambda\"" ], "sourceUrls": [ "https://www.nacalaiusa.com/products/view/214/", "https://loginsg.idtdna.com/pages/products/reagents-and-kits/oligo-length-standards", "https://www.genedirex.com/wp-content/uploads/2023/06/2023-PRODUCT-CATALOG_V3.pdf", "https://www.pop-bio.com/wp-content/uploads/2024/03/Pop-Bio-Vu-Reagent-Brochure.pdf", "https://www.bio-rad.com/sites/default/files/2023-04/Bulletin_7479.pdf", "https://www.bio-rad.com/webroot/web/pdf/lsr/literature/2015_Life_Science_Research_Product_Catalog.pdf", "https://labchem-wako.fujifilm.com/us/category/01547.html", "https://us.bioneer.com/products/laddersandmarkers/laddersselectionguide.aspx?AspxAutoDetectCookieSupport=1" ], "reason": "No manufacturer-backed match with the required exact specificity or formulation was established in recorded searches." } ], "correctedProducts": [ { "product": "lambda-pfg-ladder-n0341", "from": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-lambda-concatemer-markers-48-5-1018-kb-markers-agarose-embedded-markers", "reason": "Manufacturer confirms lambda concatemers embedded in 1% low-melting-point agarose. This is not a liquid loading-dye formulation." }, { "product": "midrange-pfg-ladder-n0342", "from": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-lambda-concatemer-and-xhoi-mixture-markers-15-291-kb-markers-agarose-embedded-markers", "reason": "Manufacturer confirms 15-291 kb mixture embedded in 1% low-melting-point agarose; distinct range and fragment composition from lambda PFG ladder." } ] }, { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-low-range-dna-ladders-loading-formulation-unspecified", "path": [ "Analysis & standards", "Molecular weight standards", "DNA ladders", "Low-range DNA ladders", "Loading formulation unspecified" ], "productCount": 0, "companies": [], "nonNebProducts": 0, "audit": [ { "categoryId": "analysis-standards-molecular-weight-standards-dna-ladders-low-range-dna-ladders-loading-formulation-unspecified", "status": "supported-candidates", "queries": [ "Molecular weight standards DNA ladders Low-range DNA ladders reagent product -site:neb.com -site:neb.cn -site:neb-online.de -site:neb-online.fr" ], "sourceUrls": [ "https://www.jenabioscience.com/molecular-biology/pcr-classics/dna-ladders/linear-scale-dna-ladders/m-202-low-range-dna-ladder" ], "reason": "Manufacturer documents support candidate function; experimental interchangeability is not established." } ], "correctedProducts": [ { "product": "low-molecular-weight-dna-ladder-n3233", "from": "analysis-standards-molecular-weight-standards-dna-ladders-low-range-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-low-range-dna-ladders-25-766-bp-low-range-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer confirms 11 fragments 25-766 bp and separately supplied loading dye." }, { "product": "jena-bioscience-low-range-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-low-range-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-low-range-dna-ladders-50-1000-bp-low-range-ladders-ready-to-load-ladders", "reason": "Official manufacturer explicitly states 11 fragments 50 bp-1 kb and ready-to-use orange/blue tracking dyes. 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"promega-nuclease-free-water", "from": "dna-genome-engineering-nucleases-structure-specific-nucleases-nuclease-free-water", "to": "laboratory-essentials-buffers-solutions-nuclease-free-water", "reason": "Corrected biological identity or reagent role" }, { "product": "qiagen-nuclease-free-water", "from": "dna-genome-engineering-nucleases-structure-specific-nucleases-nuclease-free-water", "to": "laboratory-essentials-buffers-solutions-nuclease-free-water", "reason": "Corrected biological identity or reagent role" }, { "product": "magen-nuclease-free-water-depc-free", "from": "dna-genome-engineering-nucleases-structure-specific-nucleases-nuclease-free-water", "to": "laboratory-essentials-buffers-solutions-nuclease-free-water", "reason": "Corrected biological identity or reagent role" }, { "product": "e-coli-poly-a-polymerase-m0276", "from": "rna-transcription-rna-modification-poly-a-tailing", "to": "rna-transcription-rna-modification-poly-a-tailing-poly-a-polymerase-enzymes", "reason": "Separate complete tailing kits from standalone poly(A) polymerase reagents and RNA isolation products." }, { "product": "rna-5-pyrophosphohydrolase-rpph-m0356", "from": "rna-transcription-rna-modification-rna-decapping", "to": "rna-transcription-rna-modification-rna-5-end-processing-rna-5-pyrophosphohydrolase-rpph", "reason": "Keep the named enzyme class distinct: RNA end processing reagents have different substrate specificities and end products. DcpS produces a diphosphate end and must not be pooled with monophosphate-producing reagents." }, { "product": "rnase-h-recombinant-m0297", "from": "rna-transcription-rna-processing-rnase-h", "to": "rna-transcription-rna-processing-rna-dna-hybrid-nucleases-rnase-h", "reason": "Separate RNase HII, standard RNase H and thermostable RNase H identities; RNase HII also recognizes single embedded ribonucleotides in DNA." }, { "product": "rnase-hii-recombinant-m0288", "from": "rna-transcription-rna-processing-rnase-h", "to": "rna-transcription-rna-processing-rna-dna-hybrid-nucleases-rnase-hii", "reason": "Separate RNase HII, standard RNase H and thermostable RNase H identities; RNase HII also recognizes single embedded ribonucleotides in DNA." }, { "product": "thermostable-rnase-h-m0523", "from": "rna-transcription-rna-processing-rnase-h", "to": "rna-transcription-rna-processing-rna-dna-hybrid-nucleases-thermostable-rnase-h", "reason": "Separate RNase HII, standard RNase H and thermostable RNase H identities; RNase HII also recognizes single embedded ribonucleotides in DNA." }, { "product": "ydcps-m0463", "from": "rna-transcription-rna-modification-rna-decapping", "to": "rna-transcription-rna-modification-rna-5-end-processing-dcps-decapping-enzymes", "reason": "Keep the named enzyme class distinct: RNA end processing reagents have different substrate specificities and end products. DcpS produces a diphosphate end and must not be pooled with monophosphate-producing reagents." }, { "product": "e-coli-rna-polymerase-core-enzyme-m0550", "from": "rna-transcription-in-vitro-transcription-rna-polymerases-rna-polymerase-enzymes", "to": "rna-transcription-in-vitro-transcription-rna-polymerases-e-coli-rna-polymerase-core-enzymes", "reason": "Core bacterial polymerase, bacterial holoenzyme and T3 promoter-specific polymerase are distinct catalog enzyme identities." }, { "product": "e-coli-rna-polymerase-holoenzyme-m0551", "from": "rna-transcription-in-vitro-transcription-rna-polymerases-rna-polymerase-enzymes", "to": "rna-transcription-in-vitro-transcription-rna-polymerases-e-coli-rna-polymerase-holoenzymes", "reason": "Core bacterial polymerase, bacterial holoenzyme and T3 promoter-specific polymerase are distinct catalog enzyme identities." }, { "product": "faustovirus-capping-enzyme-m2081", "from": "rna-transcription-rna-modification-rna-capping-capping-enzymes", "to": "rna-transcription-rna-modification-rna-capping-cap-0-capping-enzymes-and-systems", "reason": "Separate Cap-0 formation, cap 2′-O methylation, cap-adjacent N6 methylation and complete Cap-1 systems. Standalone methyltransferases are not complete capping systems." }, { "product": "mrna-cap-2-o-methyltransferase-m0366", "from": "rna-transcription-rna-modification-rna-capping-capping-enzymes", "to": "rna-transcription-rna-modification-rna-capping-cap-2-o-methyltransferases", "reason": "Separate Cap-0 formation, cap 2′-O methylation, cap-adjacent N6 methylation and complete Cap-1 systems. Standalone methyltransferases are not complete capping systems." }, { "product": "mrna-cap-n6-methyltransferase-m6a-m0767", "from": "rna-transcription-rna-modification-rna-capping-capping-enzymes", "to": "rna-transcription-rna-modification-rna-capping-cap-adjacent-n6-methyltransferases", "reason": "Separate Cap-0 formation, cap 2′-O methylation, cap-adjacent N6 methylation and complete Cap-1 systems. Standalone methyltransferases are not complete capping systems." }, { "product": "mrna-decapping-enzyme-m0608", "from": "rna-transcription-rna-modification-rna-decapping", "to": "rna-transcription-rna-modification-rna-5-end-processing-mrna-decapping-enzymes-producing-5-monophosphate", "reason": "Keep the named enzyme class distinct: RNA end processing reagents have different substrate specificities and end products. DcpS produces a diphosphate end and must not be pooled with monophosphate-producing reagents." }, { "product": "onetaq-one-step-rt-pcr-kit-e5315", "from": "dna-amplification-quantitative-pcr-one-step-rt-pcr", "to": "dna-amplification-endpoint-pcr-one-step-rt-pcr-one-step-rt-pcr-kits", "reason": "Manufacturer identifies an endpoint one-step RT-PCR kit, not a quantitative RT-PCR reagent." }, { "product": "rnase-4-m1284", "from": "rna-transcription-rna-processing-ribonucleases", "to": "rna-transcription-rna-processing-ribonucleases-rnase-4", "reason": "Separate distinct ribonuclease identities and the combined RNase 4 plus end-repair formulation." }, { "product": "rnase-4-digestion-and-3-end-repair-mix-m1288", "from": "rna-transcription-rna-processing-ribonucleases", "to": "rna-transcription-rna-processing-ribonucleases-rnase-4-digestion-and-end-repair-mixes", "reason": "Separate distinct ribonuclease identities and the combined RNase 4 plus end-repair formulation." }, { "product": "rnase-if-recombinant-m0243", "from": "rna-transcription-rna-processing-ribonucleases", "to": "rna-transcription-rna-processing-ribonucleases-rnase-i", "reason": "Separate distinct ribonuclease identities and the combined RNase 4 plus end-repair formulation." }, { "product": "rnase-r-m0100", "from": "rna-transcription-rna-processing-ribonucleases", "to": "rna-transcription-rna-processing-ribonucleases-rnase-r", "reason": "Separate distinct ribonuclease identities and the combined RNase 4 plus end-repair formulation." }, { "product": "shortcut-rnase-iii-recombinant-m0245", "from": "rna-transcription-rna-processing-ribonucleases", "to": "rna-transcription-rna-processing-ribonucleases-rnase-iii", "reason": "Separate distinct ribonuclease identities and the combined RNase 4 plus end-repair formulation." }, { "product": "t3-rna-polymerase-m0378", "from": "rna-transcription-in-vitro-transcription-rna-polymerases-rna-polymerase-enzymes", "to": "rna-transcription-in-vitro-transcription-rna-polymerases-t3-rna-polymerases", "reason": "Core bacterial polymerase, bacterial holoenzyme and T3 promoter-specific polymerase are distinct catalog enzyme identities." }, { "product": "vaccinia-capping-system-m2080", "from": "rna-transcription-rna-modification-rna-capping-capping-enzymes", "to": "rna-transcription-rna-modification-rna-capping-cap-0-capping-enzymes-and-systems", "reason": "Separate Cap-0 formation, cap 2′-O methylation, cap-adjacent N6 methylation and complete Cap-1 systems. Standalone methyltransferases are not complete capping systems." }, { "product": "nebnext-da-tailing-module-e6053", "from": "sequencing-epigenetics-library-preparation-components-end-repair-tailing", "to": "sequencing-epigenetics-library-preparation-components-dna-end-and-damage-repair-da-tailing-modules", "reason": "FFPE damage repair, end repair, dA-tailing and combined end repair plus dA-tailing are distinct module functions." }, { "product": "nebnext-end-repair-module-e6050", "from": "sequencing-epigenetics-library-preparation-components-end-repair-tailing", "to": "sequencing-epigenetics-library-preparation-components-dna-end-and-damage-repair-end-repair-modules", "reason": "FFPE damage repair, end repair, dA-tailing and combined end repair plus dA-tailing are distinct module functions." }, { "product": "nebnext-enzymatic-5hmc-seq-conversion-module-e3365", "from": "sequencing-epigenetics-epigenetic-analysis-enzymatic-methylation-sequencing", "to": "sequencing-epigenetics-epigenetic-analysis-5hmc-specific-enzymatic-sequencing-conversion-modules", "reason": "Separate 5hmC-specific measurement from combined 5mC and 5hmC measurement, and conversion-only modules from library preparation kits." }, { "product": "nebnext-enzymatic-5hmc-seq-kit-e3350", "from": "sequencing-epigenetics-epigenetic-analysis-enzymatic-methylation-sequencing", "to": "sequencing-epigenetics-epigenetic-analysis-5hmc-specific-enzymatic-sequencing-library-preparation-kits", "reason": "Separate 5hmC-specific measurement from combined 5mC and 5hmC measurement, and conversion-only modules from library preparation kits." }, { "product": "nebnext-enzymatic-methyl-seq-conversion-module-e7125", "from": "sequencing-epigenetics-epigenetic-analysis-enzymatic-methylation-sequencing", "to": "sequencing-epigenetics-epigenetic-analysis-combined-5mc-and-5hmc-enzymatic-sequencing-conversion-modules", "reason": "Separate 5hmC-specific measurement from combined 5mC and 5hmC measurement, and conversion-only modules from library preparation kits." }, { "product": "nebnext-enzymatic-methyl-seq-kit-e7120", "from": "sequencing-epigenetics-epigenetic-analysis-enzymatic-methylation-sequencing", "to": "sequencing-epigenetics-epigenetic-analysis-combined-5mc-and-5hmc-enzymatic-sequencing-library-preparation-kits", "reason": "Separate 5hmC-specific measurement from combined 5mC and 5hmC measurement, and conversion-only modules from library preparation kits." }, { "product": "nebnext-enzymatic-methyl-seq-v2-conversion-module-e8020", "from": "sequencing-epigenetics-epigenetic-analysis-enzymatic-methylation-sequencing", "to": "sequencing-epigenetics-epigenetic-analysis-combined-5mc-and-5hmc-enzymatic-sequencing-conversion-modules", "reason": "Separate 5hmC-specific measurement from combined 5mC and 5hmC measurement, and conversion-only modules from library preparation kits." }, { "product": "nebnext-enzymatic-methyl-seq-v2-kit-e8015", "from": "sequencing-epigenetics-epigenetic-analysis-enzymatic-methylation-sequencing", "to": "sequencing-epigenetics-epigenetic-analysis-combined-5mc-and-5hmc-enzymatic-sequencing-library-preparation-kits", "reason": "Separate 5hmC-specific measurement from combined 5mC and 5hmC measurement, and conversion-only modules from library preparation kits." }, { "product": "nebnext-ffpe-dna-repair-mix-m6630", "from": "sequencing-epigenetics-library-preparation-components-end-repair-tailing", "to": "sequencing-epigenetics-library-preparation-components-dna-end-and-damage-repair-ffpe-dna-repair-reagents", "reason": "FFPE damage repair, end repair, dA-tailing and combined end repair plus dA-tailing are distinct module functions." }, { "product": "nebnext-ffpe-dna-repair-v2-module-e7360", "from": "sequencing-epigenetics-library-preparation-components-end-repair-tailing", "to": "sequencing-epigenetics-library-preparation-components-dna-end-and-damage-repair-ffpe-dna-repair-reagents", "reason": "FFPE damage repair, end repair, dA-tailing and combined end repair plus dA-tailing are distinct module functions." }, { "product": "nebnext-high-input-poly-a-mrna-magnetic-isolation-module-e3370", "from": "rna-transcription-rna-modification-poly-a-tailing", "to": "nucleic-acid-purification-rna-purification-poly-a-mrna-purification-magnetic-bead-isolation", "reason": "This is an mRNA isolation module, not a poly(A)-adding enzyme." }, { "product": "nebnext-multiplex-small-rna-library-prep-set-for-illumina-set1-e7300", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-sequencing-adapters", "to": "sequencing-epigenetics-library-preparation-small-rna-libraries-illumina-small-rna-library-preparation-kits", "reason": "This is a small RNA library preparation set including workflow enzymes, not a standalone sequencing adapter. Index sets and included oligos still require product-level comparison." }, { "product": "nebnext-multiplex-small-rna-prep-set-for-illumina-1-48-e7560", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-sequencing-adapters", "to": "sequencing-epigenetics-library-preparation-small-rna-libraries-illumina-small-rna-library-preparation-kits", "reason": "This is a small RNA library preparation set including workflow enzymes, not a standalone sequencing adapter. Index sets and included oligos still require product-level comparison." }, { "product": "nebnext-multiplex-small-rna-prep-set-for-illumina-set1-e7300", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-sequencing-adapters", "to": "sequencing-epigenetics-library-preparation-small-rna-libraries-illumina-small-rna-library-preparation-kits", "reason": "This is a small RNA library preparation set including workflow enzymes, not a standalone sequencing adapter. Index sets and included oligos still require product-level comparison." }, { "product": "nebnext-multiplex-small-rna-prep-set-for-illumina-set2-e7580", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-sequencing-adapters", "to": "sequencing-epigenetics-library-preparation-small-rna-libraries-illumina-small-rna-library-preparation-kits", "reason": "This is a small RNA library preparation set including workflow enzymes, not a standalone sequencing adapter. Index sets and included oligos still require product-level comparison." }, { "product": "nebnext-poly-a-mrna-magnetic-isolation-module-e7490", "from": "rna-transcription-rna-modification-poly-a-tailing", "to": "nucleic-acid-purification-rna-purification-poly-a-mrna-purification-magnetic-bead-isolation", "reason": "This is an mRNA isolation module, not a poly(A)-adding enzyme." }, { "product": "nebnext-small-rna-library-prep-set-for-illumina-multiplex-compatible-e7330", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-sequencing-adapters", "to": "sequencing-epigenetics-library-preparation-small-rna-libraries-illumina-small-rna-library-preparation-kits", "reason": "This is a small RNA library preparation set including workflow enzymes, not a standalone sequencing adapter. Index sets and included oligos still require product-level comparison." }, { "product": "nebnext-ultra-ii-end-repair-da-tailing-module-e7546", "from": "sequencing-epigenetics-library-preparation-components-end-repair-tailing", "to": "sequencing-epigenetics-library-preparation-components-dna-end-and-damage-repair-combined-end-repair-and-da-tailing-modules", "reason": "FFPE damage repair, end repair, dA-tailing and combined end repair plus dA-tailing are distinct module functions." }, { "product": "bst-2-0-dna-polymerase-m0537", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-standard-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-engineered-bst-dna-polymerases", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-2-0-dna-polymerase-concentrated-m0537", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-standard-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-engineered-bst-dna-polymerases", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-2-0-warm-start-dna-polymerase-m0538", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-warm-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-warm-start-bst-dna-polymerases-standard-formulations", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-2-0-warm-start-dna-polymerase-glycerol-free-m0402", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-warm-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-warm-start-bst-dna-polymerases-glycerol-free-formulations", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-2-0-warm-start-dna-polymerase-concentrated-m0538", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-warm-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-warm-start-bst-dna-polymerases-standard-formulations", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-3-0-dna-polymerase-m0374", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-standard-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-engineered-bst-dna-polymerases-with-enhanced-reverse-transcriptase-activity", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-3-0-dna-polymerase-concentrated-m0374", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-standard-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-engineered-bst-dna-polymerases-with-enhanced-reverse-transcriptase-activity", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-dna-polymerase-m0275", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-standard-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-bst-large-fragment-dna-polymerases", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-dna-polymerase-120-000u-ml-m0275", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-standard-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-bst-large-fragment-dna-polymerases", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-dna-polymerase-full-length-m0328", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-standard-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-full-length-bst-dna-polymerases", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-xt-warm-start-dna-polymerase-m9204", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-warm-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-warm-start-bst-dna-polymerases-standard-formulations", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bst-xt-warm-start-dna-polymerase-glycerol-free-m9205", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-warm-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-warm-start-bst-dna-polymerases-glycerol-free-formulations", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "bsu-dna-polymerase-large-fragment-m0330", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-standard-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-bsu-large-fragment-dna-polymerases", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "control-lamp-primer-mix-ractin-s0164", "from": "dna-amplification-isothermal-amplification-lamp-detection-reagents", "to": "dna-amplification-isothermal-amplification-lamp-accessory-reagents-control-primer-mixes", "reason": "Control primers and fluorescent detection dyes are different reagent types." }, { "product": "lamp-fluorescent-dye-b1700", "from": "dna-amplification-isothermal-amplification-lamp-detection-reagents", "to": "dna-amplification-isothermal-amplification-lamp-accessory-reagents-fluorescent-detection-dyes", "reason": "Control primers and fluorescent detection dyes are different reagent types." }, { "product": "lyoprime-warmstart-fluorescent-lamp-rt-lamp-mix-with-udg-l4401", "from": "dna-amplification-isothermal-amplification-lamp-master-mixes-fluorescent-lamp-udg-containing-lamp-mixes", "to": "dna-amplification-isothermal-amplification-lamp-master-mixes-lyophilized-fluorescent-lamp-mixes-with-udg", "reason": "Separate the explicitly lyophilized formulation from the liquid kit; both contain UDG." }, { "product": "sars-cov-2-rapid-colorimetric-lamp-assay-kit-e2019", "from": "dna-amplification-isothermal-amplification-lamp-master-mixes-colorimetric-lamp-udg-content-unspecified", "to": "dna-amplification-targeted-assay-kits-rt-lamp-assay-kits-sars-cov-2-colorimetric-assay-kits", "reason": "This record is a complete target-specific assay kit, not a generic colorimetric LAMP master mix. This classification records catalog identity only." }, { "product": "warmstart-colorimetric-lamp-2x-master-mix-dna-rna-m1800", "from": "dna-amplification-isothermal-amplification-lamp-master-mixes-colorimetric-lamp-udg-content-unspecified", "to": "dna-amplification-isothermal-amplification-lamp-master-mixes-colorimetric-lamp-mixes-udg-content-unspecified", "reason": "Retain the generic master mix separately from complete target-specific assay kits; absence of UDG in the name alone is not proof of composition." }, { "product": "warmstart-fluorescent-lamp-rt-lamp-kit-with-udg-e1708", "from": "dna-amplification-isothermal-amplification-lamp-master-mixes-fluorescent-lamp-udg-containing-lamp-mixes", "to": "dna-amplification-isothermal-amplification-lamp-master-mixes-liquid-fluorescent-lamp-kits-with-udg", "reason": "Separate the explicitly lyophilized formulation from the liquid kit; both contain UDG." }, { "product": "rnase-b-p7817", "from": "rna-transcription-rna-processing-ribonucleases", "to": "protein-glycobiology-glycosylation-analysis-glycoprotein-standards-rnase-b-substrates", "reason": "RNase B is supplied as a glycoprotein substrate for glycosidase analysis, not as a general RNA-processing nuclease reagent." }, { "product": "invitrogen-poly-a-tailing-kit", "from": "rna-transcription-rna-modification-poly-a-tailing", "to": "rna-transcription-rna-modification-poly-a-tailing-poly-a-tailing-kits", "reason": "Separate complete tailing kits from standalone poly(A) polymerase reagents and RNA isolation products." }, { "product": "cellscript-cap-clip-acid-pyrophosphatase", "from": "rna-transcription-rna-modification-rna-decapping", "to": "rna-transcription-rna-modification-rna-5-end-processing-acid-pyrophosphatases", "reason": "Keep the named enzyme class distinct: RNA end processing reagents have different substrate specificities and end products. DcpS produces a diphosphate end and must not be pooled with monophosphate-producing reagents." }, { "product": "promega-ribonuclease-h", "from": "rna-transcription-rna-processing-rnase-h", "to": "rna-transcription-rna-processing-rna-dna-hybrid-nucleases-rnase-h", "reason": "Separate RNase HII, standard RNase H and thermostable RNase H identities; RNase HII also recognizes single embedded ribonucleotides in DNA." }, { "product": "thermo-scientific-rnase-h", "from": "rna-transcription-rna-processing-rnase-h", "to": "rna-transcription-rna-processing-rna-dna-hybrid-nucleases-rnase-h", "reason": "Separate RNase HII, standard RNase H and thermostable RNase H identities; RNase HII also recognizes single embedded ribonucleotides in DNA." }, { "product": "promega-t3-rna-polymerase", "from": "rna-transcription-in-vitro-transcription-rna-polymerases-rna-polymerase-enzymes", "to": "rna-transcription-in-vitro-transcription-rna-polymerases-t3-rna-polymerases", "reason": "Core bacterial polymerase, bacterial holoenzyme and T3 promoter-specific polymerase are distinct catalog enzyme identities." }, { "product": "thermo-scientific-t3-rna-polymerase", "from": "rna-transcription-in-vitro-transcription-rna-polymerases-rna-polymerase-enzymes", "to": "rna-transcription-in-vitro-transcription-rna-polymerases-t3-rna-polymerases", "reason": "Core bacterial polymerase, bacterial holoenzyme and T3 promoter-specific polymerase are distinct catalog enzyme identities." }, { "product": "cellscript-scriptcap-cap-1-capping-system", "from": "rna-transcription-rna-modification-rna-capping-capping-enzymes", "to": "rna-transcription-rna-modification-rna-capping-complete-cap-1-capping-systems", "reason": "Separate Cap-0 formation, cap 2′-O methylation, cap-adjacent N6 methylation and complete Cap-1 systems. Standalone methyltransferases are not complete capping systems." }, { "product": "thermo-scientific-vaccinia-capping-enzyme", "from": "rna-transcription-rna-modification-rna-capping-capping-enzymes", "to": "rna-transcription-rna-modification-rna-capping-cap-0-capping-enzymes-and-systems", "reason": "Separate Cap-0 formation, cap 2′-O methylation, cap-adjacent N6 methylation and complete Cap-1 systems. Standalone methyltransferases are not complete capping systems." }, { "product": "thermo-scientific-vaccinia-mrna-cap-2-o-methyltransferase", "from": "rna-transcription-rna-modification-rna-capping-capping-enzymes", "to": "rna-transcription-rna-modification-rna-capping-cap-2-o-methyltransferases", "reason": "Separate Cap-0 formation, cap 2′-O methylation, cap-adjacent N6 methylation and complete Cap-1 systems. Standalone methyltransferases are not complete capping systems." }, { "product": "qiagen-qiagen-onestep-rt-pcr-kit", "from": "dna-amplification-quantitative-pcr-one-step-rt-pcr", "to": "dna-amplification-endpoint-pcr-one-step-rt-pcr-one-step-rt-pcr-kits", "reason": "Manufacturer identifies an endpoint one-step RT-PCR kit, not a quantitative RT-PCR reagent." }, { "product": "bioline-mytaq-one-step-rt-pcr-kit", "from": "dna-amplification-quantitative-pcr-one-step-rt-pcr", "to": "dna-amplification-endpoint-pcr-one-step-rt-pcr-one-step-rt-pcr-kits", "reason": "Manufacturer identifies an endpoint one-step RT-PCR kit, not a quantitative RT-PCR reagent." }, { "product": "lgc-biosearch-technologies-ribonuclease-r-rnase-r", "from": "rna-transcription-rna-processing-ribonucleases", "to": "rna-transcription-rna-processing-ribonucleases-rnase-r", "reason": "Separate distinct ribonuclease identities and the combined RNase 4 plus end-repair formulation." }, { "product": "lgc-biosearch-technologies-hybridase-thermostable-rnase-h", "from": "rna-transcription-rna-processing-rnase-h", "to": "rna-transcription-rna-processing-rna-dna-hybrid-nucleases-thermostable-rnase-h", "reason": "Separate RNase HII, standard RNase H and thermostable RNase H identities; RNase HII also recognizes single embedded ribonucleotides in DNA." }, { "product": "sbs-genetech-bst-dna-polymerase-large-fragment", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-standard-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-bst-large-fragment-dna-polymerases", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "excellgen-bst-dna-polymerase-large-fragment", "from": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-standard-start-polymerases", "to": "dna-amplification-isothermal-amplification-strand-displacing-polymerases-bst-large-fragment-dna-polymerases", "reason": "Separate Bsu, full-length Bst, native Bst large fragment and engineered Bst identities. Full-length Bst retains 5′ exonuclease activity absent from its large fragment. Formulation and reverse-transcriptase capability remain explicit rather than asserting full interchangeability." }, { "product": "nebexpress-ni-spin-columns-s1427", "from": "laboratory-essentials-labware-purification-columns", "to": "laboratory-essentials-labware-purification-columns-nickel-affinity-spin-columns-for-his-tagged-proteins", "reason": "Officially prepacked nickel affinity columns with agarose support and buffers for His-tagged proteins, not silica nucleic acid purification columns." }, { "product": "cryogenic-cold-storage-box-t1041", "from": "laboratory-essentials-labware-tubes-accessories", "to": "laboratory-essentials-labware-tubes-accessories-81-position-fiberboard-freezer-boxes", "reason": "Officially an 81-position fiberboard box for 1 to 2 mL tubes, not tubes themselves. Not specified for liquid nitrogen." }, { "product": "monarch-2-ml-tubes-t3003", "from": "laboratory-essentials-labware-tubes-accessories", "to": "laboratory-essentials-labware-tubes-accessories-2-ml-microcentrifuge-tubes-color-and-purity-grade-unspecified", "reason": "Catalog identifies 2 mL microcentrifuge tubes. Low-binding surface, cap closure, purity grade and rotor compatibility still require product-specific review. Color and purity grade have not been established for this exact catalog record; do not infer these from the product family." }, { "product": "monarch-bead-retainers-t3004", "from": "laboratory-essentials-labware-tubes-accessories", "to": "laboratory-essentials-labware-tubes-accessories-membrane-free-glass-bead-retainers", "reason": "Officially plastic retainers without a membrane, sized for the manufacturer collection tubes. These are neither tubes nor purification membranes." }, { "product": "monarch-dna-capture-beads-t3005", "from": "nucleic-acid-purification-purification-components-magnetic-capture-beads", "to": "nucleic-acid-purification-purification-components-nonmagnetic-dna-capture-beads-4-mm-borosilicate-glass-beads", "reason": "Official page explicitly identifies 4 mm borosilicate glass beads. The original magnetic-bead parent was chemically incorrect." }, { "product": "monarch-gdna-binding-buffer-t3014", "from": "laboratory-essentials-buffers-solutions-binding-buffers", "to": "laboratory-essentials-buffers-solutions-binding-buffers-formulation-compatibility-unspecified", "reason": "The official page identifies the buffer purpose, but a complete independently comparable formulation and cross-kit substitution have not been established. This is an explicitly provisional grouping, not an equivalence assertion." }, { "product": "monarch-gdna-blood-lysis-buffer-t3013", "from": "laboratory-essentials-buffers-solutions-lysis-buffers", "to": "laboratory-essentials-buffers-solutions-lysis-buffers-whole-blood-genomic-dna-lysis-formulation-compatibility-unspecified", "reason": "Officially a blood lysis component for genomic DNA extraction, distinct from selective red-cell lysis. Proprietary formulation equivalence remains unverified." }, { "product": "monarch-gdna-cell-lysis-buffer-t3012", "from": "laboratory-essentials-buffers-solutions-lysis-buffers", "to": "laboratory-essentials-buffers-solutions-lysis-buffers-cell-genomic-dna-lysis-formulation-compatibility-unspecified", "reason": "Officially the cell-lysis component of a genomic DNA extraction kit. Proprietary formulation equivalence remains unverified." }, { "product": "monarch-gdna-elution-buffer-t3016", "from": "laboratory-essentials-buffers-solutions-elution-buffers", "to": "laboratory-essentials-buffers-solutions-elution-buffers-formulation-compatibility-unspecified", "reason": "The official page identifies the buffer purpose, but a complete independently comparable formulation and cross-kit substitution have not been established. This is an explicitly provisional grouping, not an equivalence assertion." }, { "product": "monarch-gdna-elution-buffer-ii-t3056", "from": "laboratory-essentials-buffers-solutions-elution-buffers", "to": "laboratory-essentials-buffers-solutions-elution-buffers-10-mm-tris-0-5-mm-edta-ph-9-0", "reason": "Official product page explicitly discloses 10 mM Tris, 0.5 mM EDTA, pH 9.0. Match buffer chemistry rather than the generic elution label." }, { "product": "monarch-gdna-nuclei-prep-lysis-buffer-pack-t3054", "from": "laboratory-essentials-buffers-solutions-lysis-buffers", "to": "laboratory-essentials-buffers-solutions-lysis-buffers-nuclei-preparation-and-lysis-buffer-sets-formulation-compatibility-unspecified", "reason": "This is a two-buffer pack containing separate nuclei preparation and nuclei lysis reagents, not a single generic lysis solution." }, { "product": "monarch-gdna-purification-columns-t3017", "from": "laboratory-essentials-labware-purification-columns", "to": "laboratory-essentials-labware-purification-columns-silica-columns-binding-capacity-unspecified", "reason": "Official page identifies a proprietary silica matrix for binding genomic DNA and use in DNA depletion during RNA purification; no column-specific binding capacity established in the page." }, { "product": "monarch-gdna-tissue-lysis-buffer-t3011", "from": "laboratory-essentials-buffers-solutions-lysis-buffers", "to": "laboratory-essentials-buffers-solutions-lysis-buffers-tissue-genomic-dna-lysis-formulation-compatibility-unspecified", "reason": "Officially the tissue-lysis component of a genomic DNA extraction kit. Proprietary formulation equivalence remains unverified." }, { "product": "monarch-gdna-wash-buffer-t3015", "from": "laboratory-essentials-buffers-solutions-wash-buffers", "to": "laboratory-essentials-buffers-solutions-wash-buffers-formulation-compatibility-unspecified", "reason": "The official page identifies the buffer purpose, but a complete independently comparable formulation and cross-kit substitution have not been established. This is an explicitly provisional grouping, not an equivalence assertion." }, { "product": "monarch-hmw-gdna-tissue-lysis-buffer-t3061", "from": "laboratory-essentials-buffers-solutions-lysis-buffers", "to": "laboratory-essentials-buffers-solutions-lysis-buffers-high-molecular-weight-dna-tissue-lysis-formulation-compatibility-unspecified", "reason": "Officially a tissue-lysis component for HMW DNA extraction. Proprietary formulation equivalence remains unverified." }, { "product": "monarch-mag-beads-m2-t4105", "from": "nucleic-acid-purification-purification-components-magnetic-capture-beads", "to": "nucleic-acid-purification-purification-components-magnetic-capture-beads-silica-coated-magnetic-beads", "reason": "Official product page explicitly identifies silica-coated, superparamagnetic beads. Do not pool with carboxylated cleanup beads." }, { "product": "monarch-pestle-set-t3000", "from": "laboratory-essentials-labware-homogenization-tools", "to": "laboratory-essentials-labware-homogenization-tools-single-sample-pestles", "reason": "Catalog identifies individual microtube pestles or pestle-and-tube sets, distinct from 8-channel and 96-well tools. Exact tube fit requires review." }, { "product": "monarch-rbc-lysis-buffer-t3051", "from": "laboratory-essentials-buffers-solutions-lysis-buffers", "to": "laboratory-essentials-buffers-solutions-lysis-buffers-selective-red-blood-cell-lysis-formulation-compatibility-unspecified", "reason": "Official product identity is selective erythrocyte lysis with leukocytes preserved, distinct from total blood or tissue lysis. Cross-manufacturer formulation equivalence remains unverified." }, { "product": "monarch-spin-collection-tubes-t2118", "from": "laboratory-essentials-labware-tubes-accessories", "to": "laboratory-essentials-labware-tubes-accessories-collection-tubes-color-and-purity-grade-unspecified", "reason": "Officially 2 mL collection tubes for spin columns. Dimensional compatibility must be confirmed for another column. Color and purity grade have not been established for this exact catalog record; do not infer these from the product family." }, { "product": "monarch-spin-columns-s1a-and-tubes-t2037", "from": "laboratory-essentials-labware-purification-columns", "to": "laboratory-essentials-labware-purification-columns-silica-columns-5-g-dna-10-g-rna-capacity-reported-elution-5-l", "reason": "Official page reports application-dependent 5 to 10 µg nucleic acid capacity and minimum 5 µl elution; kit association establishes 5 µg DNA and 10 µg RNA. Do not use the existing ≥6 µl or ≥10 µl leaf." }, { "product": "monarch-spin-columns-s2a-and-tubes-t2047", "from": "laboratory-essentials-labware-purification-columns", "to": "laboratory-essentials-labware-purification-columns-silica-columns-50-g-rna-capacity", "reason": "Official page identifies a silica-membrane column supplied with the 50 µg RNA cleanup kit. DNA capacity is not inferred from another manufacturer column." }, { "product": "monarch-spin-columns-s2b-and-tubes-t2057", "from": "laboratory-essentials-labware-purification-columns", "to": "laboratory-essentials-labware-purification-columns-silica-columns-500-g-rna-capacity-reported-elution-50-l", "reason": "Official silica-column page and linked RNA capacity FAQ establish 500 µg RNA capacity and 50 µl minimum elution." }, { "product": "monarch-spin-columns-s2d-and-tubes-t1117", "from": "laboratory-essentials-labware-purification-columns", "to": "laboratory-essentials-labware-purification-columns-silica-columns-plasmid-purification-columns-reported-elution-30-l", "reason": "Official page identifies the column included with plasmid miniprep kit T1110 and minimum 30 µl elution. Kit yield is not equated to independently measured column capacity." }, { "product": "monarch-spin-columns-s3a-and-tubes-t1157", "from": "laboratory-essentials-labware-purification-columns", "to": "laboratory-essentials-labware-purification-columns-silica-columns-100-g-dna-capacity-reported-elution-50-l", "reason": "Official page identifies the column supplied with the 100 µg DNA cleanup kit and ≥50 µl elution, unlike existing 25 µl and 150 µl leaves." }, { "product": "monarch-spin-columns-s3b-and-tubes-t2067", "from": "laboratory-essentials-labware-purification-columns", "to": "laboratory-essentials-labware-purification-columns-silica-columns-3-mg-rna-capacity", "reason": "Official S3B page reports RNA cleanup capacity up to 3 mg per column. Do not confuse with 3 mg DNA columns." }, { "product": "monarch-spin-high-capacity-dna-cleanup-kit-100-g-t1135", "from": "nucleic-acid-purification-dna-purification-pcr-cleanup-spin-column-purification", "to": "nucleic-acid-purification-dna-purification-pcr-cleanup-spin-column-purification-reported-capacity-100-g-dna", "reason": "Manufacturer explicitly reports up to 100 µg DNA purification. Fragment range and elution specification remain product-specific comparison attributes." }, { "product": "monarch-spin-high-capacity-rna-cleanup-kit-3-mg-t2060", "from": "nucleic-acid-purification-rna-purification-rna-cleanup-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-rna-cleanup-spin-column-purification-reported-capacity-3-mg-rna", "reason": "Official product identity and capacity FAQ specify 3 mg RNA cleanup capacity. Do not place these different load capacities together solely because small RNA cleanup may be supported." }, { "product": "monarch-spin-pcr-dna-cleanup-kit-5ug-t1130", "from": "nucleic-acid-purification-dna-purification-pcr-cleanup-spin-column-purification", "to": "nucleic-acid-purification-dna-purification-pcr-cleanup-spin-column-purification-reported-capacity-5-g-dna", "reason": "Manufacturer explicitly reports up to 5 µg DNA purification. Fragment range and elution specification remain product-specific comparison attributes." }, { "product": "monarch-spin-plasmid-miniprep-kit-t1110", "from": "nucleic-acid-purification-dna-purification-plasmid-minipreps-spin-column-purification", "to": "nucleic-acid-purification-dna-purification-plasmid-minipreps-spin-column-purification-reported-yield-up-to-20-g-plasmid-dna", "reason": "Manufacturer reports plasmid yield up to 20 µg. This is a yield specification, not a claim of binding capacity. Keep separate from the 100 µg capacity leaf." }, { "product": "monarch-spin-rna-cleanup-kit-10-g-t2030", "from": "nucleic-acid-purification-rna-purification-rna-cleanup-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-rna-cleanup-spin-column-purification-reported-capacity-10-g-rna", "reason": "Official product identity and capacity FAQ specify 10 µg RNA cleanup capacity. Do not place these different load capacities together solely because small RNA cleanup may be supported." }, { "product": "monarch-spin-rna-cleanup-kit-50-g-t2040", "from": "nucleic-acid-purification-rna-purification-rna-cleanup-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-rna-cleanup-spin-column-purification-reported-capacity-50-g-rna", "reason": "Official product identity and capacity FAQ specify 50 µg RNA cleanup capacity. Do not place these different load capacities together solely because small RNA cleanup may be supported." }, { "product": "neb-tube-opener-c1008", "from": "laboratory-essentials-labware-tubes-accessories", "to": "laboratory-essentials-labware-tubes-accessories-microcentrifuge-tube-openers", "reason": "Official page identifies a tool for opening snap and screw caps, not consumable tubes." }, { "product": "qiagen-qiaquick-pcr-purification-kit", "from": "nucleic-acid-purification-dna-purification-pcr-cleanup-spin-column-purification", "to": "nucleic-acid-purification-dna-purification-pcr-cleanup-spin-column-purification-reported-capacity-10-g-dna", "reason": "Manufacturer explicitly reports up to 10 µg DNA purification. Fragment range and elution specification remain product-specific comparison attributes." }, { "product": "qiagen-qiaprep-spin-miniprep-kit", "from": "nucleic-acid-purification-dna-purification-plasmid-minipreps-spin-column-purification", "to": "nucleic-acid-purification-dna-purification-plasmid-minipreps-spin-column-purification-reported-yield-up-to-20-g-plasmid-dna", "reason": "Manufacturer reports plasmid yield up to 20 µg. This is a yield specification, not a claim of binding capacity. Keep separate from the 100 µg capacity leaf." }, { "product": "zymo-research-urine-conditioning-buffer", "from": "nucleic-acid-purification-sample-preservation-urine-stabilization-reagents", "to": "nucleic-acid-purification-sample-preservation-urine-stabilization-reagents-dna-and-rna-stabilization-formulations-requiring-review", "reason": "Official product page confirms both DNA and RNA preservation in urine. Proprietary formulation and substitution with another stabilizer remain unverified." }, { "product": "zymo-research-zr-plasmid-miniprep-classic", "from": "nucleic-acid-purification-dna-purification-plasmid-minipreps-spin-column-purification", "to": "nucleic-acid-purification-dna-purification-plasmid-minipreps-spin-column-purification-reported-yield-up-to-25-g-plasmid-dna", "reason": "Manufacturer reports plasmid yield up to 25 µg. This is a yield specification, not a claim of binding capacity. Keep separate from the 100 µg capacity leaf." }, { "product": "zymo-research-zyppy-plasmid-miniprep-kit", "from": "nucleic-acid-purification-dna-purification-plasmid-minipreps-spin-column-purification", "to": "nucleic-acid-purification-dna-purification-plasmid-minipreps-spin-column-purification-reported-yield-up-to-25-g-plasmid-dna", "reason": "Manufacturer reports plasmid yield up to 25 µg. This is a yield specification, not a claim of binding capacity. Keep separate from the 100 µg capacity leaf." }, { "product": "zymo-research-zymopure-express-plasmid-midiprep-kit", "from": "nucleic-acid-purification-dna-purification-plasmid-midipreps-spin-column-purification", "to": "nucleic-acid-purification-dna-purification-plasmid-midipreps-spin-column-purification-reported-capacity-1-2-mg-dna", "reason": "Official specification table reports 1.2 mg binding capacity. Typical yield is a separate specification." }, { "product": "zymo-research-onestep-plus-qmethyl-pcr-kit", "from": "sequencing-epigenetics-epigenetic-analysis-restriction-based-dna-methylation-quantification", "to": "sequencing-epigenetics-epigenetic-analysis-restriction-based-dna-methylation-quantification-complete-restriction-sensitive-qpcr-methylation-kits", "reason": "Official D5312 is a full methylation quantification kit with test and reference reagents, not either legacy premix alone." }, { "product": "promega-binding-buffer-bbf", "from": "laboratory-essentials-buffers-solutions-binding-buffers", "to": "laboratory-essentials-buffers-solutions-binding-buffers-formulation-compatibility-unspecified", "reason": "The official page identifies the buffer purpose, but a complete independently comparable formulation and cross-kit substitution have not been established. This is an explicitly provisional grouping, not an equivalence assertion." }, { "product": "promega-elution-buffer", "from": "laboratory-essentials-buffers-solutions-elution-buffers", "to": "laboratory-essentials-buffers-solutions-elution-buffers-formulation-compatibility-unspecified", "reason": "The official page identifies the buffer purpose, but a complete independently comparable formulation and cross-kit substitution have not been established. This is an explicitly provisional grouping, not an equivalence assertion." }, { "product": "magen-dna-elution-buffer-ph-8-5", "from": "laboratory-essentials-buffers-solutions-elution-buffers", "to": "laboratory-essentials-buffers-solutions-elution-buffers-formulation-compatibility-unspecified", "reason": "The official page identifies the buffer purpose, but a complete independently comparable formulation and cross-kit substitution have not been established. This is an explicitly provisional grouping, not an equivalence assertion." }, { "product": "dwk-life-sciences-kimble-disposable-pellet-pestle-tissue-grinder", "from": "laboratory-essentials-labware-homogenization-tools", "to": "laboratory-essentials-labware-homogenization-tools-single-sample-pestles", "reason": "Catalog identifies individual microtube pestles or pestle-and-tube sets, distinct from 8-channel and 96-well tools. Exact tube fit requires review." }, { "product": "eppendorf-eppendorf-safe-lock-tubes-2-0-ml", "from": "laboratory-essentials-labware-tubes-accessories", "to": "laboratory-essentials-labware-tubes-accessories-2-ml-microcentrifuge-tubes-color-and-purity-grade-unspecified", "reason": "Catalog identifies 2 mL microcentrifuge tubes. Low-binding surface, cap closure, purity grade and rotor compatibility still require product-specific review. Color and purity grade have not been established for this exact catalog record; do not infer these from the product family." }, { "product": "3-0-me-7mg-ppp-g-rna-cap-structure-analog-arca-s1411", "from": "rna-transcription-rna-modification-rna-capping-cap-analogs", "to": "rna-transcription-rna-modification-rna-capping-cap-analogs-anti-reverse-dinucleotide-cap-analogs-arca", "reason": "ARCA identity is distinct from conventional m7G dinucleotides and unmethylated G analogs. Shared identity supports candidate comparison; purity and concentration remain product-specific." }, { "product": "3-o-me-7mg-ppp-g-rna-cap-structure-analog-arca-s1411", "from": "rna-transcription-rna-modification-rna-capping-cap-analogs", "to": "rna-transcription-rna-modification-rna-capping-cap-analogs-anti-reverse-dinucleotide-cap-analogs-arca", "reason": "ARCA identity is distinct from conventional m7G dinucleotides and unmethylated G analogs. Shared identity supports candidate comparison; purity and concentration remain product-specific." }, { "product": "rna-cap-struc-analog-g-5-ppp-5-a-s1406", "from": "rna-transcription-rna-modification-rna-capping-cap-analogs", "to": "rna-transcription-rna-modification-rna-capping-cap-analogs-g-5-ppp-5-a-dinucleotide-cap-analogs", "reason": "Exact official catalog chemistry distinguishes N7 methylation and the second nucleotide; these are not chemically equivalent to ARCA or each other." }, { "product": "rna-cap-struc-analog-g-5-ppp-5-g-s1407", "from": "rna-transcription-rna-modification-rna-capping-cap-analogs", "to": "rna-transcription-rna-modification-rna-capping-cap-analogs-g-5-ppp-5-g-dinucleotide-cap-analogs", "reason": "Exact official catalog chemistry distinguishes N7 methylation and the second nucleotide; these are not chemically equivalent to ARCA or each other." }, { "product": "rna-cap-struc-analog-m7g-5-ppp-5-a-s1405", "from": "rna-transcription-rna-modification-rna-capping-cap-analogs", "to": "rna-transcription-rna-modification-rna-capping-cap-analogs-m7g-5-ppp-5-a-dinucleotide-cap-analogs", "reason": "Exact official catalog chemistry distinguishes N7 methylation and the second nucleotide; these are not chemically equivalent to ARCA or each other." }, { "product": "rna-cap-struc-analog-m7g-5-ppp-5-g-s1404", "from": "rna-transcription-rna-modification-rna-capping-cap-analogs", "to": "rna-transcription-rna-modification-rna-capping-cap-analogs-m7g-5-ppp-5-g-dinucleotide-cap-analogs", "reason": "Exact official catalog chemistry distinguishes N7 methylation and the second nucleotide; these are not chemically equivalent to ARCA or each other." }, { "product": "nebnext-globin-rrna-depletion-kit-human-mouse-rat-e7750", "from": "sequencing-epigenetics-rna-sequencing-rrna-depletion", "to": "sequencing-epigenetics-rna-sequencing-rrna-depletion-human-mouse-rat-rrna-and-globin-depletion-purification-beads-supplied-separately", "reason": "Manufacturer catalog distinguishes target groups and inclusion of cleanup beads. Globin depletion is not equivalent to rRNA-only depletion, and bacterial probes are not mammalian probes." }, { "product": "nebnext-globin-rrna-depletion-kit-human-mouse-rat-with-beads-e7755", "from": "sequencing-epigenetics-rna-sequencing-rrna-depletion", "to": "sequencing-epigenetics-rna-sequencing-rrna-depletion-human-mouse-rat-rrna-and-globin-depletion-purification-beads-included", "reason": "Manufacturer catalog distinguishes target groups and inclusion of cleanup beads. Globin depletion is not equivalent to rRNA-only depletion, and bacterial probes are not mammalian probes." }, { "product": "nebnext-lv-unique-dual-index-primers-set-1-e3400", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-low-volume-udi-primer-pairs", "reason": "Official low-volume primer family differs from adapter-containing oligo sets. Sets remain comparison candidates, but index sequences and pooling combinations must be checked." }, { "product": "nebnext-lv-unique-dual-index-primers-set-2-e3402", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-low-volume-udi-primer-pairs", "reason": "Official low-volume primer family differs from adapter-containing oligo sets. Sets remain comparison candidates, but index sequences and pooling combinations must be checked." }, { "product": "nebnext-lv-unique-dual-index-primers-set-2a-e3390", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-low-volume-udi-primer-pairs", "reason": "Official low-volume primer family differs from adapter-containing oligo sets. Sets remain comparison candidates, but index sequences and pooling combinations must be checked." }, { "product": "nebnext-lv-unique-dual-index-primers-set-2b-e3392", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-low-volume-udi-primer-pairs", "reason": "Official low-volume primer family differs from adapter-containing oligo sets. Sets remain comparison candidates, but index sequences and pooling combinations must be checked." }, { "product": "nebnext-lv-unique-dual-index-primers-set-3-e3404", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-low-volume-udi-primer-pairs", "reason": "Official low-volume primer family differs from adapter-containing oligo sets. Sets remain comparison candidates, but index sequences and pooling combinations must be checked." }, { "product": "nebnext-lv-unique-dual-index-primers-set-4-e3406", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-low-volume-udi-primer-pairs", "reason": "Official low-volume primer family differs from adapter-containing oligo sets. Sets remain comparison candidates, but index sequences and pooling combinations must be checked." }, { "product": "nebnext-lv-unique-dual-index-primers-set-5-e3408", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-low-volume-udi-primer-pairs", "reason": "Official low-volume primer family differs from adapter-containing oligo sets. Sets remain comparison candidates, but index sequences and pooling combinations must be checked." }, { "product": "nebnext-multiplex-oligos-for-illumin-96-unique-dual-index-primer-pairs-e6440", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-udi-primer-sets-with-loop-adapters", "reason": "Official oligo family includes 8-base unique index primer pairs and a loop adapter. Do not pool with low-volume primer-only sets or ligatable UDI-UMI adapters." }, { "product": "nebnext-multiplex-oligos-for-illumina-96-unique-dual-index-primer-pairs-set-2-e6442", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-udi-primer-sets-with-loop-adapters", "reason": "Official oligo family includes 8-base unique index primer pairs and a loop adapter. Do not pool with low-volume primer-only sets or ligatable UDI-UMI adapters." }, { "product": "nebnext-multiplex-oligos-for-illumina-96-unique-dual-index-primer-pairs-set-3-e6444", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-udi-primer-sets-with-loop-adapters", "reason": "Official oligo family includes 8-base unique index primer pairs and a loop adapter. Do not pool with low-volume primer-only sets or ligatable UDI-UMI adapters." }, { "product": "nebnext-multiplex-oligos-for-illumina-96-unique-dual-index-primer-pairs-set-4-e6446", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-udi-primer-sets-with-loop-adapters", "reason": "Official oligo family includes 8-base unique index primer pairs and a loop adapter. Do not pool with low-volume primer-only sets or ligatable UDI-UMI adapters." }, { "product": "nebnext-multiplex-oligos-for-illumina-96-unique-dual-index-primer-pairs-set-5-e6448", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-udi-primer-sets-with-loop-adapters", "reason": "Official oligo family includes 8-base unique index primer pairs and a loop adapter. Do not pool with low-volume primer-only sets or ligatable UDI-UMI adapters." }, { "product": "nebnext-multiplex-oligos-for-illumina-96-unique-dual-index-primer-pairs-e6440", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-udi-primer-sets-with-loop-adapters", "reason": "Official oligo family includes 8-base unique index primer pairs and a loop adapter. Do not pool with low-volume primer-only sets or ligatable UDI-UMI adapters." }, { "product": "nebnext-multiplex-oligos-for-illumina-unique-dual-index-umi-adaptors-dna-set-1-e7395", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-udi-umi-ligation-adapters-for-dna-libraries", "reason": "Catalog expressly designates DNA-library UMI adapters. Keep distinct from RNA-library sets and indexing PCR primers." }, { "product": "nebnext-multiplex-oligos-for-illumina-unique-dual-index-umi-adaptors-dna-set-2-e7874", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-udi-umi-ligation-adapters-for-dna-libraries", "reason": "Catalog expressly designates DNA-library UMI adapters. Keep distinct from RNA-library sets and indexing PCR primers." }, { "product": "nebnext-multiplex-oligos-for-illumina-unique-dual-index-umi-adaptors-dna-set-3-e7876", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-udi-umi-ligation-adapters-for-dna-libraries", "reason": "Catalog expressly designates DNA-library UMI adapters. Keep distinct from RNA-library sets and indexing PCR primers." }, { "product": "nebnext-multiplex-oligos-for-illumina-unique-dual-index-umi-adaptors-dna-set-4-e7878", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-udi-umi-ligation-adapters-for-dna-libraries", "reason": "Catalog expressly designates DNA-library UMI adapters. Keep distinct from RNA-library sets and indexing PCR primers." }, { "product": "nebnext-multiplex-oligos-for-illumina-unique-dual-index-umi-adaptors-rna-set-1-e7416", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-udi-umi-ligation-adapters-for-rna-derived-libraries", "reason": "Catalog expressly designates RNA-library UMI adapters. Keep distinct from DNA-library adapter sets and indexing PCR primers." }, { "product": "nebnext-multiplex-oligos-for-illumina-set-3-96-unique-dual-index-primer-pairs-e6444", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-8-base-udi-primer-sets-with-loop-adapters", "reason": "Official oligo family includes 8-base unique index primer pairs and a loop adapter. Do not pool with low-volume primer-only sets or ligatable UDI-UMI adapters." }, { "product": "nebnext-rna-depletion-core-reagent-set-e7865", "from": "sequencing-epigenetics-rna-sequencing-rrna-depletion", "to": "sequencing-epigenetics-rna-sequencing-rrna-depletion-depletion-enzyme-and-buffer-components-without-probes", "reason": "Official E7865 requires a separately supplied probe pool. It is not a complete species-targeted depletion kit." }, { "product": "nebnext-rrna-depletion-kit-bacteria-e7850", "from": "sequencing-epigenetics-rna-sequencing-rrna-depletion", "to": "sequencing-epigenetics-rna-sequencing-rrna-depletion-bacterial-rrna-depletion-purification-beads-supplied-separately", "reason": "Manufacturer catalog distinguishes target groups and inclusion of cleanup beads. Globin depletion is not equivalent to rRNA-only depletion, and bacterial probes are not mammalian probes." }, { "product": "nebnext-rrna-depletion-kit-bacteria-with-rna-sample-purification-beads-e7860", "from": "sequencing-epigenetics-rna-sequencing-rrna-depletion", "to": "sequencing-epigenetics-rna-sequencing-rrna-depletion-bacterial-rrna-depletion-purification-beads-included", "reason": "Manufacturer catalog distinguishes target groups and inclusion of cleanup beads. Globin depletion is not equivalent to rRNA-only depletion, and bacterial probes are not mammalian probes." }, { "product": "nebnext-rrna-depletion-kit-v2-human-mouse-rat-e7400", "from": "sequencing-epigenetics-rna-sequencing-rrna-depletion", "to": "sequencing-epigenetics-rna-sequencing-rrna-depletion-human-mouse-rat-rrna-depletion-purification-beads-supplied-separately", "reason": "Manufacturer catalog distinguishes target groups and inclusion of cleanup beads. Globin depletion is not equivalent to rRNA-only depletion, and bacterial probes are not mammalian probes." }, { "product": "nebnext-rrna-depletion-kit-v2-human-mouse-rat-with-beads-e7405", "from": "sequencing-epigenetics-rna-sequencing-rrna-depletion", "to": "sequencing-epigenetics-rna-sequencing-rrna-depletion-human-mouse-rat-rrna-depletion-purification-beads-included", "reason": "Manufacturer catalog distinguishes target groups and inclusion of cleanup beads. Globin depletion is not equivalent to rRNA-only depletion, and bacterial probes are not mammalian probes." }, { "product": "monarch-spin-rna-isolation-kit-mini-t2110", "from": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification-small-rna-retaining-cell-and-tissue-extraction-reported-rna-size-20-nt", "reason": "Official T2110 manual states total RNA ≥20 nt, including small RNAs. Keep apart from >200 nt extraction products." }, { "product": "qiagen-rneasy-mini-kit", "from": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification-rna-longer-than-200-nt-cell-and-tissue-miniprep-kits", "reason": "Official RNeasy specification table states total RNA >200 nt. This is not equivalent to kits claiming retention of small RNA." }, { "product": "qiagen-rneasy-plant-mini-kit", "from": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-plant-rna-extraction-spin-column-purification-plant-total-rna-kits", "reason": "Official kit is formulated for plant input rather than generic mammalian cells and tissue." }, { "product": "qiagen-rneasy-ffpe-kit", "from": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-ffpe-rna-extraction-spin-column-purification-ffpe-rna-extraction-kits", "reason": "Official kit is for fixed paraffin-embedded tissue and must be separated from fresh-sample extraction kits." }, { "product": "zymo-research-zymo-seq-udi-primer-sets", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-udi-primers-for-truseq-adapter-structure-with-variant-unspecified", "reason": "Manufacturer expressly supports TruSeq adapter structure and excludes Nextera. Aggregate record covers different index lengths and presentations; exact variant needs selection." }, { "product": "zymo-research-quick-rna-microprep-kit", "from": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification-small-rna-retaining-cell-and-tissue-extraction-reported-rna-size-17-nt-reported-binding-capacity-10-g", "reason": "Official product specification reports total RNA ≥17 nt and 10 µg binding capacity. Micro, mini and midi capacity classes are distinct. Miniprep and Miniprep Plus remain candidates for overlapping cell/tissue inputs, with extra sample-specific compatibility reviewed individually." }, { "product": "zymo-research-quick-rna-miniprep-kit", "from": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification-small-rna-retaining-cell-and-tissue-extraction-reported-rna-size-17-nt-reported-binding-capacity-100-g", "reason": "Official product specification reports total RNA ≥17 nt and 100 µg binding capacity. Micro, mini and midi capacity classes are distinct. Miniprep and Miniprep Plus remain candidates for overlapping cell/tissue inputs, with extra sample-specific compatibility reviewed individually." }, { "product": "zymo-research-quick-rna-midiprep-kit", "from": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification-small-rna-retaining-cell-and-tissue-extraction-reported-rna-size-17-nt-reported-binding-capacity-1-mg", "reason": "Official product specification reports total RNA ≥17 nt and 1 mg binding capacity. Micro, mini and midi capacity classes are distinct. Miniprep and Miniprep Plus remain candidates for overlapping cell/tissue inputs, with extra sample-specific compatibility reviewed individually." }, { "product": "zymo-research-quick-rna-miniprep-plus-kit", "from": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-rna-extraction-spin-column-purification-small-rna-retaining-cell-and-tissue-extraction-reported-rna-size-17-nt-reported-binding-capacity-100-g", "reason": "Official product specification reports total RNA ≥17 nt and 100 µg binding capacity. Micro, mini and midi capacity classes are distinct. Miniprep and Miniprep Plus remain candidates for overlapping cell/tissue inputs, with extra sample-specific compatibility reviewed individually." }, { "product": "trilink-biotechnologies-arca", "from": "rna-transcription-rna-modification-rna-capping-cap-analogs", "to": "rna-transcription-rna-modification-rna-capping-cap-analogs-anti-reverse-dinucleotide-cap-analogs-arca", "reason": "ARCA identity is distinct from conventional m7G dinucleotides and unmethylated G analogs. Shared identity supports candidate comparison; purity and concentration remain product-specific." }, { "product": "jena-bioscience-arca-cap-analog-solution", "from": "rna-transcription-rna-modification-rna-capping-cap-analogs", "to": "rna-transcription-rna-modification-rna-capping-cap-analogs-anti-reverse-dinucleotide-cap-analogs-arca", "reason": "ARCA identity is distinct from conventional m7G dinucleotides and unmethylated G analogs. Shared identity supports candidate comparison; purity and concentration remain product-specific." }, { "product": "illumina-illumina-ribo-zero-plus-rrna-depletion-kit", "from": "sequencing-epigenetics-rna-sequencing-rrna-depletion", "to": "sequencing-epigenetics-rna-sequencing-rrna-depletion-mixed-mammalian-and-bacterial-rrna-plus-globin-depletion-kits", "reason": "Official Ribo-Zero Plus documentation identifies one reagent targeting mammalian rRNA and globin plus E. coli and B. subtilis rRNA; target coverage differs from single-group kits." }, { "product": "integrated-dna-technologies-xgen-udi-primers", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-udi-primers-for-stubby-adapters-with-variant-unspecified", "reason": "Official IDT family includes indexing primers used with stubby adapters. Exact 8 nt versus 10 nt variant and concentration are not established for this aggregate record." }, { "product": "integrated-dna-technologies-xgen-udi-umi-adapters", "from": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes", "to": "sequencing-epigenetics-library-preparation-components-indexes-adapters-unique-dual-indexes-illumina-libraries-udi-umi-ta-ligation-adapters-requiring-strand-orientation-review", "reason": "IDT specifies TA-ligation compatibility and a stranded RNA-library orientation difference from standard TruSeq adapters. Do not equate this family to all other UMI adapters." }, { "product": "zymo-research-quick-rna-ffpe-miniprep", "from": "nucleic-acid-purification-rna-purification-ffpe-rna-extraction-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-ffpe-rna-extraction-spin-column-purification-ffpe-rna-extraction-kits", "reason": "Official product page identifies an RNA extraction kit for FFPE tissue, including deparaffinization reagent. This is a same-function candidate for the existing FFPE kit leaf, subject to size retention and sample requirements." }, { "product": "zymo-research-quick-rna-plant-kit", "from": "nucleic-acid-purification-rna-purification-plant-rna-extraction-spin-column-purification", "to": "nucleic-acid-purification-rna-purification-plant-rna-extraction-spin-column-purification-plant-total-rna-kits-retaining-small-rna", "reason": "Official product page expressly states total plant RNA including small and micro RNAs. Preserve this verified retention distinction from plant RNA kits without a matching claim." }, { "product": "nebnext-adaptor-dilution-buffer-b1430", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-other-reaction-specific-buffers-nebnext-adaptor-dilution-buffer", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-other-reaction-specific-buffers-adapter-dilution-buffers-formulation-compatibility-requires-review", "reason": "Officially intended for sequencing-adapter dilution. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "nebnext-da-tailing-reaction-buffer-b6059", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-other-reaction-specific-buffers-nebnext-da-tailing-reaction-buffer", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-other-reaction-specific-buffers-10x-da-tailing-buffers-formulation-compatibility-requires-review", "reason": "Officially a 10X buffer for exonuclease-deficient Klenow dA-tailing. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "nebnext-dsdna-fragmentase-reaction-buffer-v2-b0349", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-nuclease-buffers-nebnext-dsdna-fragmentase-reaction-buffer-v2", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-nuclease-buffers-10x-enzymatic-dsdna-fragmentation-buffers-formulation-compatibility-requires-review", "reason": "Officially a 10X buffer for the specified dsDNA fragmentation enzyme mixture. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "nebnext-end-repair-reaction-buffer-b6052", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-other-reaction-specific-buffers-nebnext-end-repair-reaction-buffer", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-other-reaction-specific-buffers-10x-dna-end-repair-buffers-formulation-compatibility-requires-review", "reason": "Official page explicitly excludes compatibility with the newer Ultra II system; an end-repair role alone does not establish substitution. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "nebnext-library-dilution-buffer-b6118", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-other-reaction-specific-buffers-nebnext-library-dilution-buffer", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-other-reaction-specific-buffers-10x-library-quantification-dilution-buffers-formulation-compatibility-requires-review", "reason": "Officially dilutes libraries for the named library quantification kits, distinct from adapter dilution. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "nebnext-quick-ligation-reaction-buffer-5x-b6058", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-ligation-buffers-nebnext-quick-ligation-reaction-buffer-5x", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-ligation-buffers-5x-rapid-dna-ligation-buffers-formulation-compatibility-requires-review", "reason": "Officially a 5X ligation buffer; manufacturer explicitly excludes Ultra compatibility. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "nebnext-second-strand-synthesis-dntp-free-reaction-buffer-b6117", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-other-reaction-specific-buffers-nebnext-second-strand-synthesis-dntp-free-reaction-buffer", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-other-reaction-specific-buffers-10x-dntp-free-second-strand-synthesis-buffers-formulation-compatibility-requires-review", "reason": "Officially a 10X second-strand synthesis buffer without dNTPs. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "q5-reaction-buffer-pack-b9027", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-amplification-buffers-q5-reaction-buffer-pack", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-amplification-buffers-5x-high-fidelity-pcr-buffer-packs-formulation-compatibility-requires-review", "reason": "Officially a buffer pack for the specified high-fidelity polymerase family. Compatibility with other polymerases is not established. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "monarch-buffer-b1-t1112", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-buffer-b1", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-plasmid-lysis-buffers-formulation-compatibility-requires-review", "reason": "Official T1112 product page identifies Buffer B2 as a plasmid lysis buffer. Correct erroneous B1 display name while retaining original product ID and packs. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "monarch-buffer-b1-t1113", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-buffer-b1", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-plasmid-neutralization-buffers-formulation-compatibility-requires-review", "reason": "Official T1113 product page identifies Buffer B3 as a plasmid neutralization buffer. Correct erroneous B1 display name while retaining original product ID and packs. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "monarch-buffer-b1-t1111", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-buffer-b1", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-plasmid-resuspension-buffers-without-rnase-a-formulation-compatibility-requires-review", "reason": "Official B1 page identifies resuspension buffer supplied without RNase A. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "monarch-buffer-bx-t2041", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-buffer-bx", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-guanidine-based-nucleic-acid-binding-buffers-formulation-compatibility-requires-review", "reason": "Official BX page identifies a guanidine-based binding buffer. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "monarch-buffer-by-t1121", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-buffer-by", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-dna-gel-dissolving-buffers-formulation-compatibility-requires-review", "reason": "Official BY page identifies the gel-dissolving role. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "monarch-buffer-bz-t1114", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-buffer-bz", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-dna-cleanup-binding-and-plasmid-first-wash-buffers-formulation-compatibility-requires-review", "reason": "Official BZ page specifies both DNA cleanup binding and plasmid wash-1 roles. These are workflow-dependent functions of one formulation. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "monarch-buffer-wx-t2042", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-buffer-wx", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-nucleic-acid-wash-buffers-formulation-compatibility-requires-review", "reason": "Official WX page identifies a nucleic acid wash buffer; full formulation equivalence is unverified. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "monarch-buffer-wz-t1115", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-buffer-wz", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-nucleic-acid-wash-buffers-formulation-compatibility-requires-review", "reason": "Official WZ page identifies wash-2 for plasmid purification and wash buffer for other DNA and RNA kits; full formulation equivalence to WX or other wash buffers is unverified. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "monarch-stabilyse-dna-rna-buffer-t2111", "from": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-monarch-stabilyse-dna-rna-buffer", "to": "laboratory-essentials-buffers-solutions-reaction-buffers-purification-buffers-dna-and-rna-stabilization-and-lysis-buffers-formulation-compatibility-requires-review", "reason": "Official page identifies combined preservation, storage and lysis functions. Manufacturer-specific compatibility remains in product metadata, not the category name. This provisional leaf does not assert interchangeability." }, { "product": "5-deadenylase-m0331", "from": "dna-genome-engineering-end-modification-adenylation-deadenylation", "to": "dna-genome-engineering-end-modification-5-prime-deadenylation-enzymes", "reason": "Opposite biochemical transformations must not share an interchangeable-product category." }, { "product": "9n-reverse-gyrase-m0200", "from": "dna-genome-engineering-dna-topology-topoisomerases", "to": "dna-genome-engineering-dna-topology-reverse-gyrases", "reason": "Distinct topology enzymes have different biochemical activities; separate the documented enzyme identities." }, { "product": "afu-uracil-dna-glycosylase-udg-m0279", "from": "dna-genome-engineering-dna-repair-uracil-excision", "to": "dna-genome-engineering-dna-repair-uracil-excision-thermostable-uracil-dna-glycosylases", "reason": "Separate inhibition from uracil excision and preserve declared thermal/activation differences." }, { "product": "antarctic-thermolabile-udg-m0372", "from": "dna-genome-engineering-dna-repair-uracil-excision", "to": "dna-genome-engineering-dna-repair-uracil-excision-thermolabile-uracil-dna-glycosylases", "reason": "Separate inhibition from uracil excision and preserve declared thermal/activation differences." }, { "product": "ape-1-recombinant-m0282", "from": "dna-genome-engineering-dna-repair-dna-repair-enzymes", "to": "dna-genome-engineering-dna-repair-dna-repair-enzymes-ape1-ap-endonuclease", "reason": "Separate individual repair enzyme identities and distinct multi-enzyme repair mixtures; broad DNA repair activity is insufficient for substitution." }, { "product": "authenticase-m0689", "from": "dna-genome-engineering-dna-repair-dna-repair-enzymes", "to": "dna-genome-engineering-dna-repair-dna-repair-enzymes-mismatch-cleaving-nuclease-mixtures", "reason": "Manufacturer identifies proprietary mixture of structure-specific nucleases for mismatches and indels, distinct from individual repair glycosylases." }, { "product": "cas9-nuclease-s-pyogenes-m0386", "from": "dna-genome-engineering-crispr-genome-editing-cas9-reagents", "to": "dna-genome-engineering-crispr-genome-editing-cas9-reagents-spcas9-nucleases", "reason": "Separate catalytically inactive, nicking, ortholog and named engineered Cas 9 variants instead of treating all Cas 9 reagents as interchangeable." }, { "product": "cas9-nuclease-s-pyogenes-concentrated-m0386", "from": "dna-genome-engineering-crispr-genome-editing-cas9-reagents", "to": "dna-genome-engineering-crispr-genome-editing-cas9-reagents-spcas9-nucleases", "reason": "Separate catalytically inactive, nicking, ortholog and named engineered Cas 9 variants instead of treating all Cas 9 reagents as interchangeable." }, { "product": "dna-gyrase-e-coli-m7636", "from": "dna-genome-engineering-dna-topology-topoisomerases", "to": "dna-genome-engineering-dna-topology-dna-gyrases", "reason": "Distinct topology enzymes have different biochemical activities; separate the documented enzyme identities." }, { "product": "dna-polymerase-i-m0209", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases-dna-polymerase-i", "reason": "T4, T7 and DNA polymerase I are distinct enzymes; shared DNA synthesis activity alone does not establish substitution." }, { "product": "dna-polymerase-large-fragment-klenow-m0210", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments-klenow-fragment-with-proofreading-exonuclease", "reason": "Preserve the declared exonuclease-positive versus exonuclease-minus identity." }, { "product": "engen-sau-cas9-m0654", "from": "dna-genome-engineering-crispr-genome-editing-cas9-reagents", "to": "dna-genome-engineering-crispr-genome-editing-cas9-reagents-sacas9-nucleases", "reason": "Separate catalytically inactive, nicking, ortholog and named engineered Cas 9 variants instead of treating all Cas 9 reagents as interchangeable." }, { "product": "engen-seq1-cas9-m0668", "from": "dna-genome-engineering-crispr-genome-editing-cas9-reagents", "to": "dna-genome-engineering-crispr-genome-editing-cas9-reagents-seq1-cas9-variants", "reason": "Separate catalytically inactive, nicking, ortholog and named engineered Cas 9 variants instead of treating all Cas 9 reagents as interchangeable." }, { "product": "engen-spry-cas9-m0669", "from": "dna-genome-engineering-crispr-genome-editing-cas9-reagents", "to": "dna-genome-engineering-crispr-genome-editing-cas9-reagents-spry-cas9-nucleases", "reason": "Separate catalytically inactive, nicking, ortholog and named engineered Cas 9 variants instead of treating all Cas 9 reagents as interchangeable." }, { "product": "engen-spy-cas9-hf1-m0667", "from": "dna-genome-engineering-crispr-genome-editing-cas9-reagents", "to": "dna-genome-engineering-crispr-genome-editing-cas9-reagents-high-fidelity-spcas9-hf1-nucleases", "reason": "Separate catalytically inactive, nicking, ortholog and named engineered Cas 9 variants instead of treating all Cas 9 reagents as interchangeable." }, { "product": "engen-spy-cas9-nickase-m0650", "from": "dna-genome-engineering-crispr-genome-editing-cas9-reagents", "to": "dna-genome-engineering-crispr-genome-editing-cas9-reagents-spcas9-nickases", "reason": "Separate catalytically inactive, nicking, ortholog and named engineered Cas 9 variants instead of treating all Cas 9 reagents as interchangeable." }, { "product": "engen-spy-cas9-nls-m0646", "from": "dna-genome-engineering-crispr-genome-editing-cas9-reagents", "to": "dna-genome-engineering-crispr-genome-editing-cas9-reagents-spcas9-nucleases-with-nls", "reason": "Separate catalytically inactive, nicking, ortholog and named engineered Cas 9 variants instead of treating all Cas 9 reagents as interchangeable." }, { "product": "engen-spy-dcas9-snap-tag-m0652", "from": "dna-genome-engineering-crispr-genome-editing-cas9-reagents", "to": "dna-genome-engineering-crispr-genome-editing-cas9-reagents-inactive-spcas9-snap-tag-fusion", "reason": "Separate catalytically inactive, nicking, ortholog and named engineered Cas 9 variants instead of treating all Cas 9 reagents as interchangeable." }, { "product": "et-ssb-extreme-thermostable-ssbinding-protein-m2401", "from": "dna-genome-engineering-dna-binding-proteins-single-stranded-dna-binding", "to": "dna-genome-engineering-dna-binding-proteins-single-stranded-dna-binding-extreme-thermostable-single-stranded-dna-binding-proteins", "reason": "Separate the documented thermostable SSB and T4 gene 32 protein identities." }, { "product": "fpg-m0240", "from": "dna-genome-engineering-dna-repair-base-excision-repair", "to": "dna-genome-engineering-dna-repair-base-excision-repair-fpg-dna-glycosylase", "reason": "Base-excision repair includes different lesion specificities and mixtures. Split by named enzyme/function and declared thermal variant." }, { "product": "haag-human-alkyladenine-glycosylase-m0313", "from": "dna-genome-engineering-dna-repair-dna-repair-enzymes", "to": "dna-genome-engineering-dna-repair-dna-repair-enzymes-human-alkyladenine-dna-glycosylase", "reason": "Separate individual repair enzyme identities and distinct multi-enzyme repair mixtures; broad DNA repair activity is insufficient for substitution." }, { "product": "hi-t4-dna-ligase-m2622", "from": "dna-genome-engineering-ligation-t4-dna-ligases-liquid-enzymes", "to": "dna-genome-engineering-ligation-t4-dna-ligases-thermostability-enhanced-t4-dna-ligases", "reason": "Retain explicitly engineered thermostability variant separately from standard soluble ligase." }, { "product": "hsmug2-m0336", "from": "dna-genome-engineering-dna-repair-base-excision-repair", "to": "dna-genome-engineering-dna-repair-base-excision-repair-smug1-dna-glycosylase", "reason": "Official NEB product M0336 is hSMUG1; supplied catalog hSMUG2 is a source-name typo. Preserve original pack description for provenance." }, { "product": "immobilized-t4-dna-ligase-m0569", "from": "dna-genome-engineering-ligation-t4-dna-ligases-liquid-enzymes", "to": "dna-genome-engineering-ligation-t4-dna-ligases-immobilized-enzymes", "reason": "Manufacturer describes magnetic-bead immobilization, not a soluble liquid ligase formulation." }, { "product": "klenow-fragment-3-5-exo-m0212", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments-klenow-fragment-without-proofreading-exonuclease", "reason": "Preserve the declared exonuclease-positive versus exonuclease-minus identity." }, { "product": "salt-t4-dna-ligase-m0467", "from": "dna-genome-engineering-ligation-t4-dna-ligases-liquid-enzymes", "to": "dna-genome-engineering-ligation-t4-dna-ligases-salt-tolerance-enhanced-t4-dna-ligases", "reason": "Retain explicitly engineered salt-tolerance variant separately from standard soluble ligase." }, { "product": "t4-dna-polymerase-m0203", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases-t4-dna-polymerase", "reason": "T4, T7 and DNA polymerase I are distinct enzymes; shared DNA synthesis activity alone does not establish substitution." }, { "product": "t4-gene-32-protein-m0300", "from": "dna-genome-engineering-dna-binding-proteins-single-stranded-dna-binding", "to": "dna-genome-engineering-dna-binding-proteins-single-stranded-dna-binding-t4-gene-32-protein", "reason": "Separate the documented thermostable SSB and T4 gene 32 protein identities." }, { "product": "t7-dna-polymerase-unmodified-m0274", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases-t7-dna-polymerase", "reason": "T4, T7 and DNA polymerase I are distinct enzymes; shared DNA synthesis activity alone does not establish substitution." }, { "product": "tela-protelomerase-m0621", "from": "dna-genome-engineering-dna-topology-protelomerases", "to": "dna-genome-engineering-dna-topology-protelomerases-tela-protelomerase", "reason": "TelA and TelN have distinct recognition specificities; use separate enzyme identity categories." }, { "product": "teln-protelomerase-m0768", "from": "dna-genome-engineering-dna-topology-protelomerases", "to": "dna-genome-engineering-dna-topology-protelomerases-teln-protelomerase", "reason": "TelA and TelN have distinct recognition specificities; use separate enzyme identity categories." }, { "product": "thermolabile-user-ii-enzyme-m5508", "from": "dna-genome-engineering-dna-repair-base-excision-repair", "to": "dna-genome-engineering-dna-repair-base-excision-repair-thermolabile-uracil-excision-mixtures", "reason": "Base-excision repair includes different lesion specificities and mixtures. Split by named enzyme/function and declared thermal variant." }, { "product": "thermostable-ogg-m0464", "from": "dna-genome-engineering-dna-repair-base-excision-repair", "to": "dna-genome-engineering-dna-repair-base-excision-repair-thermostable-ogg-glycosylase", "reason": "Base-excision repair includes different lesion specificities and mixtures. Split by named enzyme/function and declared thermal variant." }, { "product": "thermostable-user-iii-enzyme-m5509", "from": "dna-genome-engineering-dna-repair-base-excision-repair", "to": "dna-genome-engineering-dna-repair-base-excision-repair-thermostable-uracil-excision-mixtures", "reason": "Base-excision repair includes different lesion specificities and mixtures. Split by named enzyme/function and declared thermal variant." }, { "product": "thymine-dna-glycosylase-tdg-m0766", "from": "dna-genome-engineering-dna-repair-dna-repair-enzymes", "to": "dna-genome-engineering-dna-repair-dna-repair-enzymes-thymine-dna-glycosylase", "reason": "Separate individual repair enzyme identities and distinct multi-enzyme repair mixtures; broad DNA repair activity is insufficient for substitution." }, { "product": "topoisomerase-i-e-coli-recombinant-m0301", "from": "dna-genome-engineering-dna-topology-topoisomerases", "to": "dna-genome-engineering-dna-topology-dna-topoisomerase-i", "reason": "Distinct topology enzymes have different biochemical activities; separate the documented enzyme identities." }, { "product": "uracil-glycosylase-inhibitor-m0281", "from": "dna-genome-engineering-dna-repair-uracil-excision", "to": "dna-genome-engineering-dna-repair-uracil-excision-uracil-dna-glycosylase-inhibitors", "reason": "Separate inhibition from uracil excision and preserve declared thermal/activation differences." }, { "product": "uracil-dna-glycosylase-udg-m0280", "from": "dna-genome-engineering-dna-repair-uracil-excision", "to": "dna-genome-engineering-dna-repair-uracil-excision-standard-uracil-dna-glycosylases", "reason": "Separate inhibition from uracil excision and preserve declared thermal/activation differences." }, { "product": "user-enzyme-recombinant-m5505", "from": "dna-genome-engineering-dna-repair-base-excision-repair", "to": "dna-genome-engineering-dna-repair-base-excision-repair-uracil-specific-excision-mixtures", "reason": "Base-excision repair includes different lesion specificities and mixtures. Split by named enzyme/function and declared thermal variant." }, { "product": "warmstart-afu-uracil-dna-glycosylase-udg-m1282", "from": "dna-genome-engineering-dna-repair-uracil-excision", "to": "dna-genome-engineering-dna-repair-uracil-excision-warm-start-thermostable-uracil-dna-glycosylases", "reason": "Separate inhibition from uracil excision and preserve declared thermal/activation differences." }, { "product": "5-dna-adenylation-kit-e2610", "from": "dna-genome-engineering-end-modification-adenylation-deadenylation", "to": "dna-genome-engineering-end-modification-5-prime-adenylation-kits", "reason": "Opposite biochemical transformations must not share an interchangeable-product category." }, { "product": "precr-repair-mix-m0309", "from": "dna-genome-engineering-dna-repair-dna-repair-enzymes", "to": "dna-genome-engineering-dna-repair-dna-repair-enzymes-dna-repair-enzyme-mixtures", "reason": "Separate individual repair enzyme identities and distinct multi-enzyme repair mixtures; broad DNA repair activity is insufficient for substitution." }, { "product": "sulfolobus-dna-polymerase-iv-m0327", "from": "dna-genome-engineering-dna-synthesis-labeling-specialized-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-specialized-dna-polymerases-sulfolobus-dna-polymerase-iv", "reason": "Distinct polymerase identities and engineering must not be merged because all are specialized enzymes." }, { "product": "therminator-dna-polymerase-m0261", "from": "dna-genome-engineering-dna-synthesis-labeling-specialized-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-specialized-dna-polymerases-engineered-nucleotide-analogue-incorporating-dna-polymerases", "reason": "Distinct polymerase identities and engineering must not be merged because all are specialized enzymes." }, { "product": "yeasen-t4-dna-polymerase", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases-t4-dna-polymerase", "reason": "T4, T7 and DNA polymerase I are distinct enzymes; shared DNA synthesis activity alone does not establish substitution." }, { "product": "yeasen-dna-polymerase-i", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases-dna-polymerase-i", "reason": "T4, T7 and DNA polymerase I are distinct enzymes; shared DNA synthesis activity alone does not establish substitution." }, { "product": "yeasen-klenow-fragment", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments-klenow-fragment-with-proofreading-exonuclease", "reason": "Preserve the declared exonuclease-positive versus exonuclease-minus identity." }, { "product": "yeasen-klenow-fragment-exo", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments-klenow-fragment-without-proofreading-exonuclease", "reason": "Preserve the declared exonuclease-positive versus exonuclease-minus identity." }, { "product": "yeasen-uracil-specific-excision-reagent", "from": "dna-genome-engineering-dna-repair-base-excision-repair", "to": "dna-genome-engineering-dna-repair-base-excision-repair-uracil-specific-excision-mixtures", "reason": "Base-excision repair includes different lesion specificities and mixtures. Split by named enzyme/function and declared thermal variant." }, { "product": "yeasen-cas9-nuclease", "from": "dna-genome-engineering-crispr-genome-editing-cas9-reagents", "to": "dna-genome-engineering-crispr-genome-editing-cas9-reagents-spcas9-nucleases", "reason": "Separate catalytically inactive, nicking, ortholog and named engineered Cas 9 variants instead of treating all Cas 9 reagents as interchangeable." }, { "product": "yeasen-t4-gene-32-protein", "from": "dna-genome-engineering-dna-binding-proteins-single-stranded-dna-binding", "to": "dna-genome-engineering-dna-binding-proteins-single-stranded-dna-binding-t4-gene-32-protein", "reason": "Separate the documented thermostable SSB and T4 gene 32 protein identities." }, { "product": "yeasen-teln-protelomerase", "from": "dna-genome-engineering-dna-topology-protelomerases", "to": "dna-genome-engineering-dna-topology-protelomerases-teln-protelomerase", "reason": "TelA and TelN have distinct recognition specificities; use separate enzyme identity categories." }, { "product": "apexbio-5-dna-adenylation-kit", "from": "dna-genome-engineering-end-modification-adenylation-deadenylation", "to": "dna-genome-engineering-end-modification-5-prime-adenylation-kits", "reason": "Opposite biochemical transformations must not share an interchangeable-product category." }, { "product": "cellscript-adenylator-dna-rna-5-adenylation-kit", "from": "dna-genome-engineering-end-modification-adenylation-deadenylation", "to": "dna-genome-engineering-end-modification-5-prime-adenylation-kits", "reason": "Opposite biochemical transformations must not share an interchangeable-product category." }, { "product": "qiagen-uracil-dna-glycosylase", "from": "dna-genome-engineering-dna-repair-uracil-excision", "to": "dna-genome-engineering-dna-repair-uracil-excision-standard-uracil-dna-glycosylases", "reason": "Separate inhibition from uracil excision and preserve declared thermal/activation differences." }, { "product": "solis-biodyne-salini-ung-uracil-n-glycosylase", "from": "dna-genome-engineering-dna-repair-uracil-excision", "to": "dna-genome-engineering-dna-repair-uracil-excision-thermolabile-uracil-dna-glycosylases", "reason": "Separate inhibition from uracil excision and preserve declared thermal/activation differences." }, { "product": "thermo-scientific-dna-polymerase-i", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases-dna-polymerase-i", "reason": "T4, T7 and DNA polymerase I are distinct enzymes; shared DNA synthesis activity alone does not establish substitution." }, { "product": "thermo-scientific-t4-dna-polymerase", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases-t4-dna-polymerase", "reason": "T4, T7 and DNA polymerase I are distinct enzymes; shared DNA synthesis activity alone does not establish substitution." }, { "product": "thermo-scientific-t7-dna-polymerase", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerases-t7-dna-polymerase", "reason": "T4, T7 and DNA polymerase I are distinct enzymes; shared DNA synthesis activity alone does not establish substitution." }, { "product": "thermo-scientific-klenow-fragment", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments-klenow-fragment-with-proofreading-exonuclease", "reason": "Preserve the declared exonuclease-positive versus exonuclease-minus identity." }, { "product": "thermo-scientific-klenow-fragment-exo", "from": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments", "to": "dna-genome-engineering-dna-synthesis-labeling-dna-polymerase-fragments-klenow-fragment-without-proofreading-exonuclease", "reason": "Preserve the declared exonuclease-positive versus exonuclease-minus identity." }, { "product": "thermo-scientific-uracil-dna-glycosylase-heat-labile", "from": "dna-genome-engineering-dna-repair-uracil-excision", "to": "dna-genome-engineering-dna-repair-uracil-excision-thermolabile-uracil-dna-glycosylases", "reason": "Separate inhibition from uracil excision and preserve declared thermal/activation differences." }, { "product": "sbs-genetech-9n-exo-dna-polymerase", "from": "dna-genome-engineering-dna-synthesis-labeling-specialized-dna-polymerases", "to": "dna-genome-engineering-dna-synthesis-labeling-specialized-dna-polymerases-9n-exonuclease-minus-dna-polymerase", "reason": "Distinct polymerase identities and engineering must not be merged because all are specialized enzymes." }, { "product": "yeasen-hieff-ngs-ffpe-dna-repair-reagent", "from": "dna-genome-engineering-dna-repair-dna-repair-enzymes", "to": "dna-genome-engineering-dna-repair-dna-repair-enzymes-ffpe-dna-repair-mixtures", "reason": "Separate individual repair enzyme identities and distinct multi-enzyme repair mixtures; broad DNA repair activity is insufficient for substitution." }, { "product": "inspiralis-e-coli-gyrase", "from": "dna-genome-engineering-dna-topology-topoisomerases", "to": "dna-genome-engineering-dna-topology-dna-gyrases", "reason": "Distinct topology enzymes have different biochemical activities; separate the documented enzyme identities." }, { "product": "t4-phage-beta-glucosyltransferase-m0357", "from": "cells-expression-phage-tools-helper-phages", "to": "dna-genome-engineering-dna-modification-dna-glucosylation-t4-beta-glucosyltransferase", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "e-coli-ribosome-p0763", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-cell-free-expression-translation-components-e-coli-ribosomes", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "q5-site-directed-mutagenesis-kit-without-competent-cells-e0552", "from": "cells-expression-competent-cells-cloning-e-coli-strain-unspecified", "to": "dna-genome-engineering-mutagenesis-site-directed-mutagenesis-pcr-mutagenesis-kits-without-competent-cells", "reason": "Kit explicitly excludes competent cells and must not be indexed as a competent-cell strain." }, { "product": "anti-cbd-monoclonal-antibody-e8034", "from": "protein-glycobiology-protein-detection-antibodies", "to": "protein-glycobiology-protein-detection-antibodies-anti-cbd-monoclonal-antibodies", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "anti-mbp-monoclonal-antibody-e8032", "from": "protein-glycobiology-protein-detection-antibodies", "to": "protein-glycobiology-protein-detection-antibodies-anti-mbp-monoclonal-antibodies", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "anti-snap-tag-antibody-polyclonal-p9310", "from": "protein-glycobiology-protein-detection-antibodies", "to": "protein-glycobiology-protein-detection-antibodies-anti-snap-tag-polyclonal-antibodies", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "bg-gla-nhs-s9151", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-nhs-ester-functionalized-benzylguanine", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "bg-maleimide-s9153", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-maleimide-functionalized-benzylguanine", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "bg-peg-nh2-s9150", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-amine-functionalized-peg-benzylguanine", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "clip-cell-tmr-star-s9219", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-clip-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-clip-tag-reagents-intracellular-labeling-substrates-tmr-star", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "k-lactis-protein-expression-kit-e1000", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-yeast-expression-k-lactis-expression-kits", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "nebexpress-cell-free-e-coli-protein-synthesis-system-e5360", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-cell-free-expression-in-vitro-protein-synthesis-e-coli-lysate-based-translation-systems", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "nebexpress-e-coli-lysis-reagent-p8116", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-cell-lysis-e-coli-chemical-lysis-reagents", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "nebexpress-mbp-fusion-and-purification-system-e8201", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-protein-expression-and-purification-systems-mbp-fusion-systems", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "nebexpress-t4-lysozyme-p8115", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "protein-glycobiology-protein-processing-cell-wall-hydrolases-t4-lysozyme", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "pclipf-vector-n9215", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-clip-tag-reagents", "to": "cells-expression-expression-vectors-self-labeling-tag-vectors-clip-tag-fusion-expression-vectors", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "ph-d-12-phage-display-peptide-library-kit-v2-e8210", "from": "cells-expression-phage-tools-helper-phages", "to": "cells-expression-phage-tools-phage-display-peptide-libraries-linear-12-residue-peptide-libraries-complete-library-kits", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "ph-d-12-phage-display-peptide-library-500-l-e8111", "from": "cells-expression-phage-tools-helper-phages", "to": "cells-expression-phage-tools-phage-display-peptide-libraries-linear-12-residue-peptide-libraries-library-preparations", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "ph-d-7-phage-display-peptide-library-kit-v2-e8211", "from": "cells-expression-phage-tools-helper-phages", "to": "cells-expression-phage-tools-phage-display-peptide-libraries-linear-7-residue-peptide-libraries-complete-library-kits", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "ph-d-c7c-phage-display-peptide-library-kit-v2-e8212", "from": "cells-expression-phage-tools-helper-phages", "to": "cells-expression-phage-tools-phage-display-peptide-libraries-disulfide-constrained-7-residue-peptide-libraries-complete-library-kits", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "psnap-tag-t7-2-vector-n9181", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "cells-expression-expression-vectors-self-labeling-tag-vectors-snap-tag-t7-promoter-vectors", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "psnapf-vector-n9183", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "cells-expression-expression-vectors-self-labeling-tag-vectors-snap-tag-fusion-expression-vectors", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "purexpress-delta-aa-trna-kit-e6840", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-cell-free-expression-in-vitro-protein-synthesis-defined-translation-systems-without-amino-acids-and-trna", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "purexpress-delta-rf123-kit-e6850", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-cell-free-expression-in-vitro-protein-synthesis-defined-translation-systems-without-release-factors-rf1-rf2-rf3", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "purexpress-delta-ribosome-kit-e3313", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-cell-free-expression-in-vitro-protein-synthesis-defined-translation-systems-without-ribosomes", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "purexpress-disulfide-bond-enhancer-e6820", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-cell-free-expression-translation-additives-disulfide-bond-enhancers", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "purexpress-in-vitro-protein-synthesis-kit-e6800", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-cell-free-expression-in-vitro-protein-synthesis-complete-reconstituted-e-coli-translation-systems", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "rapid-pngase-f-antibody-standard-p6043", "from": "protein-glycobiology-protein-detection-antibodies", "to": "analysis-standards-protein-standards-glycosylation-standards-pngase-f-antibody-standards", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "snap-biotin-s9110", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-biotin-labeling-substrates", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "snap-cell-430-s9109", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-intracellular-labeling-substrates-430", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-cell-505-star-s9103", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-intracellular-labeling-substrates-505-star", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-cell-647sir-s9102", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-intracellular-labeling-substrates-647sir", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-cell-block-s9106", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-intracellular-blocking-substrates", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "snap-cell-oregon-green-s9104", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-intracellular-labeling-substrates-oregon-green", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-cell-tmr-star-s9105", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-intracellular-labeling-substrates-tmr-star", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-surface-488-s9124", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-cell-surface-labeling-substrates-488", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-surface-549-s9112", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-cell-surface-labeling-substrates-549", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-surface-649-s9159", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-cell-surface-labeling-substrates-649", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-surface-alexa-fluor-488-s9129", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-cell-surface-labeling-substrates-alexa-fluor-488", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-surface-alexa-fluor-546-s9132", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-cell-surface-labeling-substrates-alexa-fluor-546", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-surface-alexa-fluor-647-s9136", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-cell-surface-labeling-substrates-alexa-fluor-647", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "snap-surface-block-s9143", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-cell-surface-blocking-substrates", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "snap-tag-purified-protein-p9312", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tag-proteins-snap-tag-purified-protein", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "monarch-microfuge-tube-ecorack-t5020", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-labware-tube-racks-microcentrifuge-tube-racks", "reason": "A microfuge tube rack is not a magnetic separation device." }, { "product": "m13k07-helper-phage-n0315", "from": "cells-expression-phage-tools-helper-phages", "to": "cells-expression-phage-tools-helper-phages-m13ko7-helper-phage", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "creative-biolabs-m13ko7-helper-phage", "from": "cells-expression-phage-tools-helper-phages", "to": "cells-expression-phage-tools-helper-phages-m13ko7-helper-phage", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "revvity-tag-lite-snap-green-labeling-reagent", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-snap-tag-reagents-labeling-substrates-with-localization-requiring-review-snap-green", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "revvity-tag-lite-clip-lumi-tb-labeling-reagent", "from": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-clip-tag-reagents", "to": "protein-glycobiology-protein-labeling-self-labeling-tags-substrates-clip-tag-reagents-labeling-substrates-with-localization-requiring-review-clip-lumi-tb", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability. Preserve fluorophore identity because detection channels and permeability differ." }, { "product": "promega-s30-t7-high-yield-protein-expression-system", "from": "cells-expression-cell-free-expression-in-vitro-protein-synthesis", "to": "cells-expression-cell-free-expression-in-vitro-protein-synthesis-e-coli-lysate-based-translation-systems", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "chromotek-anti-mbp-recombinant-vhh-unconjugated", "from": "protein-glycobiology-protein-detection-antibodies", "to": "protein-glycobiology-protein-detection-antibodies-anti-mbp-recombinant-vhh-antibodies", "reason": "Separate product roles and documented identities; a common broad application does not establish experimental interchangeability." }, { "product": "nebnext-magnetic-separation-rack-s1515", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-equipment-magnetic-separation-racks-pcr-tube-magnetic-racks-0-2-ml-tubes-24-positions", "reason": "Manufacturer vessel format and capacity constrain rack compatibility. Do not group PCR tubes, microcentrifuge tubes, conical tubes and differing plate geometries as interchangeable." }, { "product": "12-tube-magnetic-separation-rack-holds-12-tubes-s1509", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-equipment-magnetic-separation-racks-microcentrifuge-tube-magnetic-racks-1-5-ml-tubes-12-positions", "reason": "Manufacturer vessel format and capacity constrain rack compatibility. Do not group PCR tubes, microcentrifuge tubes, conical tubes and differing plate geometries as interchangeable." }, { "product": "50-ml-magnetic-separation-rack-s1507", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-equipment-magnetic-separation-racks-conical-tube-magnetic-racks-50-ml-tubes-4-positions", "reason": "Manufacturer vessel format and capacity constrain rack compatibility. Do not group PCR tubes, microcentrifuge tubes, conical tubes and differing plate geometries as interchangeable." }, { "product": "6-x-50-ml-magnetic-separation-rack-t5010", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-equipment-magnetic-separation-racks-conical-tube-magnetic-racks-50-ml-tubes-6-positions", "reason": "Manufacturer vessel format and capacity constrain rack compatibility. Do not group PCR tubes, microcentrifuge tubes, conical tubes and differing plate geometries as interchangeable." }, { "product": "96-well-microtiter-plate-magnetic-separation-rack-s1511", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-equipment-magnetic-separation-racks-plate-magnetic-racks-96-well-flat-bottom-microplates-100-300-microliter-high-flanged-plates", "reason": "Manufacturer vessel format and capacity constrain rack compatibility. Do not group PCR tubes, microcentrifuge tubes, conical tubes and differing plate geometries as interchangeable." }, { "product": "magnetic-separation-rack-for-6-tubes-holds-6-tubes-s1506", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-equipment-magnetic-separation-racks-microcentrifuge-tube-magnetic-racks-1-5-ml-tubes-6-positions", "reason": "Manufacturer vessel format and capacity constrain rack compatibility. Do not group PCR tubes, microcentrifuge tubes, conical tubes and differing plate geometries as interchangeable." }, { "product": "zymo-research-pcr-strip-magstand", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-equipment-magnetic-separation-racks-pcr-tube-magnetic-racks-tube-dimensions-require-review", "reason": "Manufacturer vessel format and capacity constrain rack compatibility. Do not group PCR tubes, microcentrifuge tubes, conical tubes and differing plate geometries as interchangeable. Direct page does not establish a unique complete geometry/capacity specification for this record; verify exact model before matching." }, { "product": "zymo-research-zr-96-magstand", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-equipment-magnetic-separation-racks-plate-magnetic-racks-96-well-plates-plate-geometry-requires-review", "reason": "Manufacturer vessel format and capacity constrain rack compatibility. Do not group PCR tubes, microcentrifuge tubes, conical tubes and differing plate geometries as interchangeable. Direct page does not establish a unique complete geometry/capacity specification for this record; verify exact model before matching." }, { "product": "thermo-scientific-magjet-separation-rack", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-equipment-magnetic-separation-racks-microcentrifuge-tube-magnetic-racks-1-5-ml-tubes-2-positions", "reason": "Manufacturer vessel format and capacity constrain rack compatibility. Do not group PCR tubes, microcentrifuge tubes, conical tubes and differing plate geometries as interchangeable." }, { "product": "sp-bel-art-magnetic-bead-separation-rack", "from": "laboratory-essentials-equipment-magnetic-separation-racks", "to": "laboratory-essentials-equipment-magnetic-separation-racks-multiple-rack-formats-requiring-sku-selection", "reason": "Manufacturer vessel format and capacity constrain rack compatibility. Do not group PCR tubes, microcentrifuge tubes, conical tubes and differing plate geometries as interchangeable. Direct page does not establish a unique complete geometry/capacity specification for this record; verify exact model before matching." }, { "product": "rna-loading-dye-2x-b0363", "from": "laboratory-essentials-electrophoresis-reagents-loading-dyes", "to": "laboratory-essentials-electrophoresis-reagents-loading-dyes-rna-loading-buffers-formamide-denaturing-buffers-bromophenol-blue-and-xylene-cyanol-with-sds", "reason": "Separate protein, RNA and DNA sample roles and documented denaturant/tracking dye/stain chemistry. Manufacturer confirms these formulation differences." }, { "product": "blue-protein-loading-dye-b7703", "from": "laboratory-essentials-electrophoresis-reagents-loading-dyes", "to": "laboratory-essentials-electrophoresis-reagents-loading-dyes-protein-loading-buffers-sds-sample-buffers-with-separate-reducing-agent", "reason": "Separate protein, RNA and DNA sample roles and documented denaturant/tracking dye/stain chemistry. Manufacturer confirms these formulation differences." }, { "product": "gel-loading-dye-blue-6x-b7021", "from": "laboratory-essentials-electrophoresis-reagents-loading-dyes", "to": "laboratory-essentials-electrophoresis-reagents-loading-dyes-dna-loading-buffers-bromophenol-blue-with-sds", "reason": "Separate protein, RNA and DNA sample roles and documented denaturant/tracking dye/stain chemistry. Manufacturer confirms these formulation differences." }, { "product": "gel-loading-dye-orange-6x-b7022", "from": "laboratory-essentials-electrophoresis-reagents-loading-dyes", "to": "laboratory-essentials-electrophoresis-reagents-loading-dyes-dna-loading-buffers-orange-g-with-sds", "reason": "Separate protein, RNA and DNA sample roles and documented denaturant/tracking dye/stain chemistry. Manufacturer confirms these formulation differences." }, { "product": "gel-loading-dye-purple-6x-b7024", "from": "laboratory-essentials-electrophoresis-reagents-loading-dyes", "to": "laboratory-essentials-electrophoresis-reagents-loading-dyes-dna-loading-buffers-uv-transparent-tracking-dyes-with-sds", "reason": "Separate protein, RNA and DNA sample roles and documented denaturant/tracking dye/stain chemistry. Manufacturer confirms these formulation differences." }, { "product": "gel-loading-dye-purple-6x-no-sds-b7025", "from": "laboratory-essentials-electrophoresis-reagents-loading-dyes", "to": "laboratory-essentials-electrophoresis-reagents-loading-dyes-dna-loading-buffers-uv-transparent-tracking-dyes-without-sds", "reason": "Separate protein, RNA and DNA sample roles and documented denaturant/tracking dye/stain chemistry. Manufacturer confirms these formulation differences." }, { "product": "thermo-scientific-rna-gel-loading-dye-2x", "from": "laboratory-essentials-electrophoresis-reagents-loading-dyes", "to": "laboratory-essentials-electrophoresis-reagents-loading-dyes-rna-loading-buffers-formamide-denaturing-buffers-bromophenol-blue-and-xylene-cyanol-with-ethidium-bromide", "reason": "Separate protein, RNA and DNA sample roles and documented denaturant/tracking dye/stain chemistry. Manufacturer confirms these formulation differences." }, { "product": "thermo-scientific-6x-dna-loading-dye-and-sds-solution", "from": "laboratory-essentials-electrophoresis-reagents-loading-dyes", "to": "laboratory-essentials-electrophoresis-reagents-loading-dyes-dna-loading-buffers-bromophenol-blue-and-xylene-cyanol-with-sds", "reason": "Separate protein, RNA and DNA sample roles and documented denaturant/tracking dye/stain chemistry. Manufacturer confirms these formulation differences." }, { "product": "kld-enzyme-mix-m0554", "from": "dna-genome-engineering-mutagenesis-site-directed-mutagenesis", "to": "dna-genome-engineering-mutagenesis-site-directed-mutagenesis-kinase-ligase-and-dpni-enzyme-components", "reason": "An enzyme component mix is not a complete mutagenesis kit." }, { "product": "q5-site-directed-mutagenesis-kit-e0554", "from": "dna-genome-engineering-mutagenesis-site-directed-mutagenesis", "to": "dna-genome-engineering-mutagenesis-site-directed-mutagenesis-pcr-mutagenesis-kits-with-competent-cells", "reason": "Manufacturer E0554 includes competent cells, unlike E0552; keep included-cell format explicit." }, { "product": "agilent-quikchange-ii-site-directed-mutagenesis-kit", "from": "dna-genome-engineering-mutagenesis-site-directed-mutagenesis", "to": "dna-genome-engineering-mutagenesis-site-directed-mutagenesis-complementary-primer-mutagenesis-kits-with-competent-cells", "reason": "QuikChange II uses a distinct complementary-primer workflow and includes XL1-Blue cells; do not imply identical primer compatibility to Q5 kit." }, { "product": "amylose-magnetic-beads-e8035", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-amylose-affinity", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-amylose-affinity-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "amylose-resin-e8021", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-amylose-affinity", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-amylose-affinity-chromatography-resin", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "amylose-resin-high-flow-e8022", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-amylose-affinity", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-amylose-affinity-high-flow-chromatography-resin", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "chitin-magnetic-beads-e8036", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-chitin-affinity", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-chitin-affinity-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "chitin-resin-s6651", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-chitin-affinity", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-chitin-affinity-chromatography-resin", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "nebexpress-ni-resin-s1428", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-other-affinity-matrices", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-nickel-affinity-chromatography-resin", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "nebexpress-ni-nta-magnetic-beads-s1423", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-other-affinity-matrices", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-nickel-nta-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "ph-d-peptide-display-cloning-system-e8101", "from": "cells-expression-phage-tools-phage-display", "to": "cells-expression-phage-tools-phage-display-m13-peptide-display-cloning-systems", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "pngase-f-p0704", "from": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f", "to": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f-standard-liquid-formulations", "reason": "Preserve rapid/reducing-state, glycerol content and removable-enzyme distinctions. These affect analytical compatibility and cannot be inferred equivalent from PNGase F identity alone." }, { "product": "pngase-f-glycerol-free-p0705", "from": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f", "to": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f-standard-liquid-formulations", "reason": "Preserve rapid/reducing-state, glycerol content and removable-enzyme distinctions. These affect analytical compatibility and cannot be inferred equivalent from PNGase F identity alone." }, { "product": "pngase-f-glycerol-free-recombinant-p0709", "from": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f", "to": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f-standard-liquid-formulations", "reason": "Preserve rapid/reducing-state, glycerol content and removable-enzyme distinctions. These affect analytical compatibility and cannot be inferred equivalent from PNGase F identity alone." }, { "product": "pngase-f-recombinant-p0708", "from": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f", "to": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f-standard-liquid-formulations", "reason": "Preserve rapid/reducing-state, glycerol content and removable-enzyme distinctions. These affect analytical compatibility and cannot be inferred equivalent from PNGase F identity alone." }, { "product": "protein-a-magnetic-beads-s1425", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-other-affinity-matrices", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-protein-a-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "protein-g-magnetic-beads-s1430", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-other-affinity-matrices", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-protein-g-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "rapid-pngase-f-p0710", "from": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f", "to": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f-rapid-formulations", "reason": "Preserve rapid/reducing-state, glycerol content and removable-enzyme distinctions. These affect analytical compatibility and cannot be inferred equivalent from PNGase F identity alone." }, { "product": "rapid-pngase-f-non-reducing-format-p0711", "from": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f", "to": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f-rapid-non-reducing-formulations", "reason": "Preserve rapid/reducing-state, glycerol content and removable-enzyme distinctions. These affect analytical compatibility and cannot be inferred equivalent from PNGase F identity alone." }, { "product": "remove-it-pngase-f-p0706", "from": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f", "to": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f-affinity-removable-enzyme-formulations", "reason": "Preserve rapid/reducing-state, glycerol content and removable-enzyme distinctions. These affect analytical compatibility and cannot be inferred equivalent from PNGase F identity alone." }, { "product": "snap-capture-magnetic-beads-s9145", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-other-affinity-matrices", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-snap-tag-capture-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "yeast-carbon-base-medium-pack-k-lactis-b9017", "from": "cells-expression-culture-media-growth-recovery-media", "to": "cells-expression-culture-media-growth-recovery-media-k-lactis-yeast-carbon-base-medium", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "oligo-d-t-25-magnetic-beads-s1419", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-other-affinity-matrices", "to": "nucleic-acid-purification-rna-purification-polyadenylated-rna-capture-oligo-dt25-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "bl21-competent-e-coli-c2530", "from": "cells-expression-competent-cells-protein-expression-e-coli-bl21-strains", "to": "cells-expression-competent-cells-protein-expression-e-coli-bl21-strains-bl21-chemically-competent-cells-without-de3", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "bl21-de3-competent-e-coli-c2527", "from": "cells-expression-competent-cells-protein-expression-e-coli-bl21-strains", "to": "cells-expression-competent-cells-protein-expression-e-coli-bl21-strains-bl21-de3-chemically-competent-cells", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "neb-10-beta-stable-outgrowth-medium-b9035", "from": "cells-expression-culture-media-growth-recovery-media", "to": "cells-expression-culture-media-growth-recovery-media-specialized-bacterial-outgrowth-medium-requiring-review", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "soc-outgrowth-medium-b9020", "from": "cells-expression-culture-media-growth-recovery-media", "to": "cells-expression-culture-media-growth-recovery-media-soc-bacterial-recovery-medium", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "t7-express-competent-e-coli-high-efficiency-c2566", "from": "cells-expression-competent-cells-protein-expression-e-coli-t7-expression-strains", "to": "cells-expression-competent-cells-protein-expression-e-coli-t7-expression-strains-t7-expression-cells-without-lysy", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "t7-express-lysy-competent-e-coli-high-efficiency-c3010", "from": "cells-expression-competent-cells-protein-expression-e-coli-t7-expression-strains", "to": "cells-expression-competent-cells-protein-expression-e-coli-t7-expression-strains-t7-expression-cells-with-lysy", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "t7-express-lysy-lq-competent-e-coli-high-efficiency-c3013", "from": "cells-expression-competent-cells-protein-expression-e-coli-t7-expression-strains", "to": "cells-expression-competent-cells-protein-expression-e-coli-t7-expression-strains-t7-expression-cells-with-lysy-and-laciq", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "advanced-biochemicals-amylose-mbp-tag-affinity-magnetic-beads", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-amylose-affinity", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-amylose-affinity-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "advanced-biochemicals-chitin-cbd-tag-affinity-magnetic-beads", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-chitin-affinity", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-chitin-affinity-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "thermo-scientific-hispur-ni-nta-magnetic-beads", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-other-affinity-matrices", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-nickel-nta-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "genovis-pngase-f", "from": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f", "to": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f-formulation-requires-review", "reason": "Preserve rapid/reducing-state, glycerol content and removable-enzyme distinctions. These affect analytical compatibility and cannot be inferred equivalent from PNGase F identity alone." }, { "product": "thermo-scientific-soc-medium", "from": "cells-expression-culture-media-growth-recovery-media", "to": "cells-expression-culture-media-growth-recovery-media-soc-bacterial-recovery-medium", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "agilent-bl21-competent-cells", "from": "cells-expression-competent-cells-protein-expression-e-coli-bl21-strains", "to": "cells-expression-competent-cells-protein-expression-e-coli-bl21-strains-bl21-chemically-competent-cells-without-de3", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "agilent-bl21-de3-competent-cells", "from": "cells-expression-competent-cells-protein-expression-e-coli-t7-expression-strains", "to": "cells-expression-competent-cells-protein-expression-e-coli-t7-expression-strains-bl21-de3-chemically-competent-cells", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "novagen-t7select10-3-cloning-kit", "from": "cells-expression-phage-tools-phage-display", "to": "cells-expression-phage-tools-phage-display-t7-peptide-display-cloning-systems", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "advanced-biochemicals-protein-a-magnetic-beads", "from": "protein-glycobiology-affinity-purification-affinity-beads-resins-other-affinity-matrices", "to": "protein-glycobiology-affinity-purification-affinity-beads-resins-protein-a-magnetic-beads", "reason": "Separate documented specificity, physical format or host-system requirements; broad application labels do not establish interchangeability." }, { "product": "rhino-bio-rhinogen-pngase-f-glycerol-free", "from": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f", "to": "protein-glycobiology-glycobiology-n-glycan-release-pngase-f-glycerol-free-formulations", "reason": "Preserve rapid/reducing-state, glycerol content and removable-enzyme distinctions. These affect analytical compatibility and cannot be inferred equivalent from PNGase F identity alone." }, { "product": "1-kb-plus-dna-ladder-n3200", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-extended-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-extended-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 100 bp to 10 kb. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "1-kb-plus-dna-ladder-for-safe-stains-n0559", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-extended-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-extended-range-1-kb-ladders-ready-to-load-ladders-optimized-for-precast-safe-stains", "reason": "Official manufacturer product page confirms premixed ready-to-load format. Reported size coverage: 100 bp to 10 kb; explicitly optimized for named precast safe stains. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "50-bp-dna-ladder-n3236", "from": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 50-1350 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "dna-ladder-1-kb-n3232", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 500 bp to 10 kb. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "dna-ladder-100-bp-n3231", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 100-1517 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "low-molecular-weight-dna-ladder-n3233", "from": "analysis-standards-molecular-weight-standards-dna-ladders-low-range-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-low-range-dna-ladders-25-766-bp-low-range-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer confirms 11 fragments 25-766 bp and separately supplied loading dye." }, { "product": "pcr-marker-n3234", "from": "analysis-standards-molecular-weight-standards-dna-ladders-pcr-size-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-pcr-size-markers-50-766-bp-sparse-pcr-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer lists five bands spanning 50-766 bp and separate loading dye. Different band pattern and upper coverage from Promega PCR markers." }, { "product": "fast-dna-ladder-n3238", "from": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-mixed-increment-dna-ladders-50-bp-to-10-kb-fast-electrophoresis-ladders-ready-to-load-ladders", "reason": "Official manufacturer product page confirms premixed ready-to-load format. Reported size coverage: 50 bp to 10 kb; 11 bands for fast electrophoresis. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "tridye-1-kb-dna-ladder-n3272", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-ready-to-load-ladders", "reason": "Official manufacturer product page confirms premixed ready-to-load format. Reported size coverage: 500 bp to 10 kb. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "tridye-1-kb-plus-dna-ladder-n3270", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-extended-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-extended-range-1-kb-ladders-ready-to-load-ladders", "reason": "Official manufacturer product page confirms premixed ready-to-load format. Reported size coverage: 100 bp to 10 kb. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "tridye-ultra-low-range-dna-ladder-n0558", "from": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-ready-to-load-ladders", "reason": "Official manufacturer product page confirms premixed ready-to-load format. Reported size coverage: 10-700 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "thermo-scientific-generuler-100-bp-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 100-1000 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "thermo-scientific-generuler-100-bp-plus-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-extended-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-extended-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 100-3000 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "thermo-scientific-generuler-1-kb-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 250 bp to 10 kb. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "thermo-scientific-generuler-1-kb-plus-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-extended-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-extended-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 75 bp to 20 kb. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "thermo-scientific-generuler-50-bp-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 50-1000 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "invitrogen-100-bp-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 100-2000 bp. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "invitrogen-1-kb-plus-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-extended-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-extended-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer product page confirms loading dye is separate or Ready to Load is No. Reported size coverage: 100 bp to 15 kb. Preserve 100 bp versus 1 kb and standard versus extended range grouping; exact band patterns still require comparison." }, { "product": "zymo-research-zr-1-kb-dna-marker", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer variant table distinguishes concentrated 500 bp to 10 kb; M5003 variants only from separately listed ready-to-load SKU. Official gel image documents the band range. Requires root removal of ready-to-load variant pack from this family record before candidate status." }, { "product": "zymo-research-zr-100-bp-dna-marker", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer variant table distinguishes concentrated 100-1500 bp; M5002 variants only from separately listed ready-to-load SKU. Official gel image documents the band range. Requires root removal of ready-to-load variant pack from this family record before candidate status." }, { "product": "zymo-research-zr-50-bp-dna-marker", "from": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-50-1200-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-50-bp-dna-ladders-50-1200-bp-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer variant table distinguishes concentrated 50-1200 bp; M5001 variants only from separately listed ready-to-load SKU. Official gel image documents the band range. Requires root removal of ready-to-load variant pack from this family record before candidate status." }, { "product": "lambda-dna-hindiii-digest-n3012", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-lambda-hindiii-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer describes eight lambda HindIII fragments, 125-23130 bp, with separate loading dye. Distinguish this band pattern from pBR322 and phiX174 digests." }, { "product": "lambda-hind-iii-digest-n3012", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-lambda-hindiii-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer describes eight lambda HindIII fragments, 125-23130 bp, with separate loading dye. Distinguish this band pattern from pBR322 and phiX174 digests." }, { "product": "promega-lambda-dna-hindiii-markers", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-lambda-hindiii-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer describes eight lambda HindIII fragments, 125-23130 bp, with separate loading dye. Distinguish this band pattern from pBR322 and phiX174 digests." }, { "product": "pbr322-bstn-i-digest-n3031", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-pbr322-bstni-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer confirms named digest, 13-1857 bp range, and separate loading dye. Digest identity determines fragment pattern." }, { "product": "pbr322-msp-i-digest-n3032", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-pbr322-mspi-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer confirms named digest, 9-622 bp range, and separate loading dye. Digest identity determines fragment pattern." }, { "product": "phi-x-174-hae-iii-digest-n3026", "from": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-restriction-digest-dna-markers-phix174-haeiii-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer confirms named digest, 72-1353 bp range, and separate loading dye. Digest identity determines fragment pattern." }, { "product": "lambda-dna-mono-cut-mix-n3019", "from": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-lambda-single-cut-mixture-markers-1-5-48-5-kb-markers-ladders-requiring-loading-dye", "reason": "Official product table documents 10 fragments from 1503 to 48502 bp and separate loading dye; not a conventional evenly incremented ladder." }, { "product": "lambda-pfg-ladder-n0341", "from": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-lambda-concatemer-markers-48-5-1018-kb-markers-agarose-embedded-markers", "reason": "Manufacturer confirms lambda concatemers embedded in 1% low-melting-point agarose. This is not a liquid loading-dye formulation." }, { "product": "midrange-pfg-ladder-n0342", "from": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-pulsed-field-dna-ladders-lambda-concatemer-and-xhoi-mixture-markers-15-291-kb-markers-agarose-embedded-markers", "reason": "Manufacturer confirms 15-291 kb mixture embedded in 1% low-melting-point agarose; distinct range and fragment composition from lambda PFG ladder." }, { "product": "supercoiled-extend-dna-ladder-n0494", "from": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-supercoiled-dna-ladders-2-15-kb-supercoiled-plasmid-ladders-ladders-requiring-loading-dye", "reason": "Official product lists nine supercoiled plasmids, 2-15 kb, and separate loading dye. Supercoiled markers must not be matched to linear DNA ladders." }, { "product": "invitrogen-supercoiled-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-dna-ladders-with-unspecified-increments-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-supercoiled-dna-ladders-2-16-kb-supercoiled-plasmid-ladders-ladders-requiring-loading-dye", "reason": "Official manufacturer MAN0001284 documents 11 plasmids, 2-16 kb, in Tris/EDTA buffer. Current official product URL returns a generic product-code page without descriptive content, so availability/direct-page confirmation remains unresolved." }, { "product": "promega-1kb-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-1-kb-dna-ladders-standard-range-1-kb-ladders-ladders-requiring-loading-dye", "reason": "Official page component table lists DNA ladder and 6 X Blue/Orange dye as separate items; fragment range 250-10000 bp. Preserve increment class and compare exact bands." }, { "product": "promega-100bp-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ladders-requiring-loading-dye", "reason": "Official page component table lists DNA ladder and 6 X Blue/Orange dye as separate items; fragment range 100-1500 bp. Preserve increment class and compare exact bands." }, { "product": "promega-pcr-markers", "from": "analysis-standards-molecular-weight-standards-dna-ladders-pcr-size-markers-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-pcr-size-markers-50-1000-bp-sparse-pcr-markers-ladders-requiring-loading-dye", "reason": "Official manufacturer lists six bands 50, 150, 300, 500, 750, 1000 bp and separate 6 X loading dye. Distinguish from NEB five-band 50-766 bp PCR marker." }, { "product": "jena-bioscience-low-range-dna-ladder", "from": "analysis-standards-molecular-weight-standards-dna-ladders-low-range-dna-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-low-range-dna-ladders-50-1000-bp-low-range-ladders-ready-to-load-ladders", "reason": "Official manufacturer explicitly states 11 fragments 50 bp-1 kb and ready-to-use orange/blue tracking dyes. Distinguish from 25-766 bp low-range ladder." }, { "product": "tridye-100-bp-dna-ladder-n3271", "from": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-loading-formulation-unspecified", "to": "analysis-standards-molecular-weight-standards-dna-ladders-100-bp-dna-ladders-standard-range-100-bp-ladders-ready-to-load-ladders", "reason": "Official product page confirms 100-1517 bp and premixed ready-to-load format with 3 tracking dyes." }, { "product": "promega-rna-markers", "from": "analysis-standards-molecular-weight-standards-rna-ladders-rna-markers-with-unspecified-strand-format", "to": "analysis-standards-molecular-weight-standards-rna-ladders-single-stranded-rna-ladders", "reason": "Manufacturer explicitly identifies nine single-stranded RNA transcripts 281-6583 nt. Strand-format uncertainty is resolved; exact band patterns remain product-specific." }, { "product": "promega-wizard-plus-midipreps-dna-purification-system", "from": "nucleic-acid-purification-dna-purification-plasmid-midipreps-spin-column-purification", "to": "nucleic-acid-purification-dna-purification-plasmid-midipreps-resin-column-purification-reported-yields-up-to-200-g-dna", "reason": "Manufacturer TB173 describes purification resin and midicolumns, with yields up to 200 µg from 10-100 ml cultures. 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"https://www.neolab.de/de/markenshop/eppendorf/pcr-multiwellplatten/multitestplatten-tuepfelplatten", "https://www.elisabeth.cz.devel.intercore.cz/produkt-twin-tec-pcr-plate-96-unskirted.html", "https://shop.buddeberg.de/life-sciences/genomics/pcr/pcr-plates-eppendorf-twintec/info824453_lang_uk.htm", "https://www.merckmillipore.com/GT/en/product/PCR-Cleanup-Filter-Plates%2CMM_NF-C7479", "https://labcorridor.com/i/14-96-well-pcr-plates-and-sealing-films/", "https://www.neolab.de/at/markenshop/eppendorf/pcr-multiwellplatten", "https://achrom.be/en/labstore/4/life-sciences/genomics/pcr/" ], "reason": "No matching 150 microliter PCR plate plus foil combination was verified.", "supportedProductCount": 0, "relatedProductCount": 0 }, { "categoryPath": [ "Laboratory essentials", "Labware", "Plate seals", "Pierceable foil seals" ], "status": "supported-candidates", "queries": [ "Labware Plate seals Pierceable foil seals manufacturer -site:zymoresearch.com -site:zymoresearch.de", "pierceable 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"https://www.azenta.com/support/product-documentation/data-sheets", "https://www.azenta.com/products/pierce-heat-seal-strong", "https://web.azenta.com/hubfs/azenta-files/resources/data-sheets/SEV-0021.pdf", "https://web.azenta.com/hubfs/azenta-files/resources/brochures-catalogs/40001-CAT-Azenta-Life-Sciences-CnI-Catalog.pdf", "https://www.azenta.com/seal-selector", "https://www.vwr.com/us/en/product/41807473/heat-sealing-foils-pierceable-azenta-life-sciences", "https://www.scientificlabs.com/en/product/pcr-seals-and-closures/PCR0562", "https://www.vwr.com/us/en/product/41807475/thermal-bond-heat-sealing-foils-polystyrene-peelable", "https://www.govsci.com/product-detail/Azenta--Life--Sciences/4TI-0566/EA/" ], "reason": "Manufacturer evidence supports candidate products within this leaf; experiment-specific interchangeability still requires comparison.", "supportedProductCount": 1, "relatedProductCount": 0 }, { "categoryPath": [ "Laboratory essentials", "Labware", "PCR plates", "96-well 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"https://www.hadalwings.com/_files/ugd/e8f8d7_7eb18692daac4206918a70fd110a5767.pdf", "https://lab-complete.com/Content/Images/uploaded/documents/Catalog/llg_labware_catalogue_edition4_uk.pdf", "https://www.aptaca.com/ENG/laboratory_testing_products/pcr_products/pcr_plates_2.php", "https://www.e-lspi.com/perform-pcr-plates-96-well-standard-02ml-per-well", "https://www.kartelllabware.com/en/products/dispolab/microbiology-and-histology/microtitre-plates/", "https://labware.opentrons.com/?loadName=biorad_96_wellplate_200ul_pcr", "https://www.azenta.com/products/non-skirted-pcr-plate-segment", "https://www.azenta.com/products/96-well-non-skirted-pcr-plate-breakable-horizontally-or-vertically", "https://www.ssibio.com/Non-Skirted-PCR-Plates", "https://www.thgeyer.com/lab/shop/pcr-plates-96-well-w/o-frame-low/brand-781366/9409247_en", "https://www.starlabgroup.com/en/product/96-well-pcr-plate-non-skirted-low-profile-natural-e1403-0200.html", "https://labwareonline.in/products/266", "https://www.starlabgroup.com/en/product/96-well-pcr-plate-non-skirted-low-profile-white-e1403-0209.html", "https://en.wikipedia.org/wiki/Microplate", "https://www.reddit.com/r/labrats/comments/1u26obp/fullskirted_pcr_plates_in_quantstudio_5_96_well/", "https://www.reddit.com/r/labrats/comments/1eqnwro/nobottom_12_well_plate_source/", "https://en.wikipedia.org/wiki/LabWare", "https://shop.llg.de/info798788_lang_uk.htm", "https://biotix.com/wp-content/uploads/2016/08/biotix_pcr_plates_spec_sheet_may_22_2015.pdf", "https://www.labunlimited.co.uk/p/pg_dl_65799/96-well-PCR-plates%2C-PP%2C-non-skirted", "https://www.starlabgroup.com/en/product/96-well-pcr-plate-non-skirted-low-profile-white-e1403-0209-c.html", "https://www.vwr.com/us/en/product/NA5274633/pcr-plates-96-well-non-skirted-azenta-life-sciences", "https://www.haeberle-lab.de/en/96-well-pcr-plates-pp-non-skirted-with-elevated-well-rim/4007896", "https://meslo.com/wp-content/uploads/2024/06/Azenta-Life-Sciences-Consumables-Instruments-Catalog_2024.pdf", "https://www.starlabgroup.com/en/mtcatalogpdf/product/index/id/1633/", "https://www.abdtest.com/PCR-Plate-02ml-Non-Skirted-p.html", "https://www.tarsons.com/product/96-well-maxiamp-pcr-plates/", "https://www.vwr.com/uk/en/product/EU2232149/pcr-plates-96--and-384-well", "https://www.usascientific.com/cms/files/PCR-Plate_Compatibility_Chart.pdf", "https://media.vwr.com/ecatalog/catalogs/33149_HSG_PCR_Solution/EN/pdf/complete_print.pdf", "https://media.starlabgroup.com/pdf/uk/literature/STARLAB-UK-Catalogue-2019-2020.pdf", "https://web.azenta.com/hubfs/azenta-files/resources/brochures-catalogs/40001-CAT-025-Individual-Access-PCR-Plates.pdf", "https://web.azenta.com/hubfs/azenta-files/resources/brochures-catalogs/40001-CAT-023-FrameStar-PCR-Plates.pdf", "https://web.azenta.com/hubfs/azenta-files/resources/brochures-flyers/40001-CAT-Azenta-Life-Sciences-CnI-Catalog.pdf", "https://www.azenta.com/products/strip-of-sealing-caps", "https://www.azenta.com/products/semi-automated-sheet-heat-sealer-formerly-intellixseal-sa" ], "reason": "Searches found several PCR plates but exact 200 microliter non-skirted configuration was not verified.", "supportedProductCount": 0, "relatedProductCount": 0 }, { "categoryPath": [ "Laboratory essentials", "Labware", "Plate seals", "Gas-permeable seals" ], "status": "no-supported-match", "queries": [ "Labware Plate seals Gas-permeable seals manufacturer -site:zymoresearch.com -site:zymoresearch.de", "\"gas permeable\" seals site:starlabgroup.com", "gas permeable seal site.azenta.com", "gas permeable seal site:azenta.com/products", "\"gas permeable\" \"seal\" site:4ti.co.uk" ], "sourceUrls": [ "https://www.merckmillipore.com/PG/en/products/labware/sample-handling/laboratory-containers-and-storage", "https://www.novolab-labware.com/gas-permeable-seals-sp-0087.html", 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