New England Biolabs
ClaI, recombinant
Read or write a reviewClaI restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
BIOLOGICAL DOMAIN
DNA & genome engineering
RM-C-04DNA engineering reagents support sequence-specific cutting, end modification, ligation, assembly and genome editing workflows.
1301 products41 manufacturers13 branches
About DNA & genome engineering
Start with the change you want to make to DNA. Restriction digestion, ligation, assembly and end modification perform different steps, while genome editing introduces additional targeting requirements. Narrower categories distinguish enzyme identity, reaction role and formulation. A shared enzyme name alone does not establish matching cleavage behavior, buffer requirements or activity units.
Choose the required molecular activity before comparing substrate specificity, reaction conditions and supplied components.
Explore 13 narrower categories
End modification
Kinases, Phosphatases, Blunt-end preparation
48 productsLigation
DNA ligases, T4 DNA ligases, RNA ligases
77 productsDNA topology
Protelomerases, Helicases, Reverse gyrases
10 productsDNA repair
Uracil excision, DNA repair enzymes, Base excision repair
32 productsCRISPR & genome editing
Cas9 reagents, Cas12 nucleases, Mutation detection
22 productsRecombination
Site-specific recombinases, Recombination proteins
8 productsDNA synthesis & labeling
DNA polymerases, DNA polymerase fragments, Terminal transferases
27 productsNucleases
DNA-degrading nucleases, Structure-specific nucleases, Exonucleases
113 productsDNA binding proteins
Single-stranded DNA binding
4 productsDNA assembly
PCR cloning, Overlap assembly, Type IIS assembly
13 productsMutagenesis
Site-directed mutagenesis
4 productsRestriction digestion
AatII restriction enzymes, Acc65I restriction enzymes, AccI restriction enzymes
942 productsDNA modification
DNA glucosylation
1 productsCompare products in this branch
1,301 products
Takara Bio
CpoI
Read or write a reviewCpoI restriction enzymes / Standard formulations
Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.
New England Biolabs
Cre Recombinase
Read or write a reviewSite-specific recombinases
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
SBS Genetech
Cre Recombinase
Read or write a reviewSite-specific recombinases
Verify substrate, formulation, activity units, buffers and experimental conditions before substitution.
Beyotime
Cre Recombinase
Read or write a reviewSite-specific recombinases
Official manufacturer catalog lists this exact named enzyme and catalog code with a product-page hyperlink. Product-page body was unavailable due to a locale redirect; verify detailed conditions with the supplier. Confirm the supplier protocol, formulation and activity units before substitution.
New England Biolabs
Cre Recombinase, conc.
Read or write a reviewSite-specific recombinases
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
Creative Biogene
Cre Recombinase, HNC
Read or write a reviewSite-specific recombinases
Verify substrate, formulation, activity units, buffers and experimental conditions before substitution.
New England Biolabs
CspCI, recombinant
Read or write a reviewCspCI restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
New England Biolabs
CviKI-1, recombinant
Read or write a reviewCviKI-1 restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
New England Biolabs
CviQI, recombinant
Read or write a reviewCviQI restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
Takara Bio
DdeI
Read or write a reviewDdeI restriction enzymes / Standard formulations
Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.
New England Biolabs
DdeI, recombinant
Read or write a reviewDdeI restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
Yeasen
Deoxyribonuclease I (DNase I) GMP-grade (2 U/μL)
Read or write a reviewDNase I / Liquid enzymes
Liquid recombinant DNase I, manufacturer-designated GMP grade. Grade and activity units require protocol review. Confirm the supplier protocol, formulation and activity units before substitution.
Zymo Research
DNA Degradase
Read or write a reviewNucleic acid digestion mixes / DNA to nucleotides
Candidate category only. Match the stated sample, material, capacity, geometry and required output before comparison; experimental interchangeability is not established.
Zymo Research
DNA Degradase Plus
Read or write a reviewNucleic acid digestion mixes / DNA to nucleosides
Candidate only. Verify activity, specificity, formulation and protocol compatibility before substitution. Digests DNA to individual nucleosides for analysis. DNA substrate only; not a universal RNA digestion replacement.
New England Biolabs
DNA Gyrase (E. coli)
Read or write a reviewDNA gyrases
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
Takara Bio
DNA Ligation Kit Mighty Mix
Read or write a reviewDNA ligases / Blunt/TA Ligase Master Mix
Verify substrate, formulation, activity units, buffers and experimental conditions before substitution.
New England Biolabs
DNA Polymerase I
Read or write a reviewDNA polymerases / DNA polymerase I
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
Yeasen
DNA Polymerase I
Read or write a reviewDNA polymerases / DNA polymerase I
Verify substrate, formulation, activity units, buffers and experimental conditions before substitution.
Thermo Scientific
DNA Polymerase I
Read or write a reviewDNA polymerases / DNA polymerase I
Verify substrate, formulation, activity units, buffers and experimental conditions before substitution.
MCLAB
DNA Polymerase I
Read or write a reviewDNA polymerases / DNA polymerase I
Full-length E. coli DNA polymerase I has polymerase and both exonuclease activities. Confirm formulation, activity units and experimental conditions before substitution.
Canvax
DNA Polymerase I (E. coli) (10 U/µL)
Read or write a reviewDNA polymerases / DNA polymerase I
Full-length E. coli DNA polymerase I with polymerase, proofreading and 5-prime exonuclease activities. Confirm formulation, activity units and experimental conditions before substitution.
New England Biolabs
DNA Polymerase Large Fragment (Klenow)
Read or write a reviewDNA polymerase fragments / Klenow fragment with proofreading exonuclease
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
New England Biolabs
DNase I (RNase-Free)
Read or write a reviewDNase I / Liquid enzymes
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
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Your selection checklist
- 01Substrate specificity and intended application
- 02Formulation, activity and concentration
- 03Protocol conditions and required components
- 04Pack size, storage and supplier documentation
ALTERNATIVE DOES NOT MEAN IDENTICAL
What to check before choosing a product
Final groups are designed around experimental substitution requirements. Group membership is provisional until the necessary technical details have been verified for the intended experiment.
Start with your application, then verify the technical requirements against each manufacturer’s documentation.
Explore manufacturer resources
Broader catalog resources for this branch. These links are discovery starting points, not verified replacements for individual products.