BIOLOGICAL DOMAIN

DNA & genome engineering

RM-C-04

Cut, join, modify and assemble DNA. Explore restriction enzymes, ligases, repair enzymes and genome editing tools.

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Research readiness

Candidate classification still requires protocol validation.

Beyotime

E. coli DNA Ligase

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DNA ligases / E. coli DNA Ligase

Official manufacturer catalog lists this exact named enzyme and catalog code with a product-page hyperlink. Product-page body was unavailable due to a locale redirect; verify detailed conditions with the supplier. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.009.001.003-0004-2D7016S1 pack optionManufacturer link
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Beyotime

E.coli DNA Polymerase I

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DNA polymerases / DNA polymerase I

Official manufacturer catalog lists this exact named enzyme and catalog code with a product-page hyperlink. Product-page body was unavailable due to a locale redirect; verify detailed conditions with the supplier. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.006.002.001-0004-1D7043S1 pack optionManufacturer link
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Takara Bio

EaeI

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EaeI restriction enzymes / Standard formulations

Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.013.157.001-0002-41123A1 pack optionManufacturer link
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Takara Bio

Eco52I

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Eco52I restriction enzymes / Standard formulations

Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.013.171.002-0001-61039A1 pack optionManufacturer link
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Thermo Scientific

Eco52I (EagI)

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Eco52I restriction enzymes / Standard formulations

Exact named-enzyme comparison candidate. Use the supplier-specific buffer, incubation temperature, activity units and inactivation protocol. Review methylation sensitivity and star activity before substitution; this is not a validated drop-in replacement.

RM-04.013.171.002-0002-4ER03321 pack optionManufacturer link
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Takara Bio

Eco81I

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Eco81I restriction enzymes / Standard formulations

Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.013.175.002-0001-21131A1 pack optionManufacturer link
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Thermo Scientific

EcoO109I

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EcoO109I restriction enzymes / Standard formulations

Same enzyme identity candidate. Verify recognition and cleavage specificity, methylation sensitivity, reaction buffer, concentration and heat inactivation in the source before substitution.

RM-04.013.179.002-0002-6ER02611 pack optionManufacturer link
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Takara Bio

EcoO109I

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EcoO109I restriction enzymes / Standard formulations

Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.013.179.002-0003-41043A1 pack optionManufacturer link
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Takara Bio

EcoO65I

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EcoO65I restriction enzymes / Standard formulations

Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.013.394.001-0001-91135A1 pack optionManufacturer link
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Your selection checklist

  • 01Substrate specificity and intended application
  • 02Formulation, activity and concentration
  • 03Protocol conditions and required components
  • 04Pack size, storage and supplier documentation

ALTERNATIVE DOES NOT MEAN IDENTICAL

What to check before choosing a product

Final groups are designed around experimental substitution requirements. Group membership is provisional until the necessary technical details have been verified for the intended experiment.

Start with your application, then verify the technical requirements against each manufacturer’s documentation.

Explore manufacturer resources

Broader catalog resources for this branch. These links are discovery starting points, not verified replacements for individual products.