BIOLOGICAL DOMAIN

DNA & genome engineering

RM-C-04

DNA engineering reagents support sequence-specific cutting, end modification, ligation, assembly and genome editing workflows.

1301 products41 manufacturers13 branches

About DNA & genome engineering

Start with the change you want to make to DNA. Restriction digestion, ligation, assembly and end modification perform different steps, while genome editing introduces additional targeting requirements. Narrower categories distinguish enzyme identity, reaction role and formulation. A shared enzyme name alone does not establish matching cleavage behavior, buffer requirements or activity units.

Choose the required molecular activity before comparing substrate specificity, reaction conditions and supplied components.

Explore 13 narrower categories

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1,301 products
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Research readiness

Candidate classification still requires protocol validation.

Takara Bio

Van91I

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Van91I restriction enzymes / Standard formulations

Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.013.369.002-0001-81193A1 pack optionManufacturer link
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Thermo Scientific

Van91I (PflMI)

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Van91I restriction enzymes / Standard formulations

Exact named-enzyme comparison candidate. Use the supplier-specific buffer, incubation temperature, activity units and inactivation protocol. Review methylation sensitivity and star activity before substitution; this is not a validated drop-in replacement.

RM-04.013.369.002-0002-6ER07121 pack optionManufacturer link
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Takara Bio

VpaK11BI

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VpaK11BI restriction enzymes / Standard formulations

Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.013.403.001-0001-81196A1 pack optionManufacturer link
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SibEnzyme

VspI Turbo

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VspI restriction enzymes / Fast-digest formulations

Same enzyme identity candidate. Verify recognition and cleavage specificity, methylation sensitivity, reaction buffer, concentration and heat inactivation in the source before substitution.

RM-04.013.370.001-0001-7E139T/E140T1 pack optionManufacturer link
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Thermo Scientific

XbaI

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XbaI restriction enzymes / Standard formulations

Same enzyme identity candidate. Verify recognition and cleavage specificity, methylation sensitivity, reaction buffer, concentration and heat inactivation in the source before substitution.

RM-04.013.373.002-0003-8ER06811 pack optionManufacturer link
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SibEnzyme

XbaI

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XbaI restriction enzymes / Standard formulations

Same enzyme identity candidate. Verify recognition and cleavage specificity, methylation sensitivity, reaction buffer, concentration and heat inactivation in the source before substitution.

RM-04.013.373.002-0002-0See manufacturer1 pack optionManufacturer link
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Jena Bioscience

XbaI

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XbaI restriction enzymes / Standard formulations

Same enzyme identity candidate. Verify recognition and cleavage specificity, methylation sensitivity, reaction buffer, concentration and heat inactivation in the source before substitution.

RM-04.013.373.002-0001-2See manufacturer1 pack optionManufacturer link
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Takara Bio

XbaI

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XbaI restriction enzymes / Standard formulations

Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.013.373.002-0006-11093A1 pack optionManufacturer link
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Promega

XbaI

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XbaI restriction enzymes / Standard formulations

Official product page specifies the named restriction enzyme and catalog number. Classified as a standard formulation; verify recognition sequence, methylation sensitivity, temperature and recommended buffer. Confirm formulation, activity units and experimental conditions before substitution.

RM-04.013.373.002-0007-9R61811 pack optionManufacturer link
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SibEnzyme

XbaI Turbo

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XbaI restriction enzymes / Fast-digest formulations

Same enzyme identity candidate. Verify recognition and cleavage specificity, methylation sensitivity, reaction buffer, concentration and heat inactivation in the source before substitution.

RM-04.013.373.001-0001-4E141T/E142T1 pack optionManufacturer link
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Thermo Scientific

XhoI

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XhoI restriction enzymes / Standard formulations

Same enzyme identity candidate. Verify recognition and cleavage specificity, methylation sensitivity, reaction buffer, concentration and heat inactivation in the source before substitution.

RM-04.013.376.002-0001-9ER06911 pack optionManufacturer link
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Takara Bio

XhoI

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XhoI restriction enzymes / Standard formulations

Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.

RM-04.013.376.002-0004-31094A1 pack optionManufacturer link
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Promega

XhoI

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XhoI restriction enzymes / Standard formulations

Official product page specifies the named restriction enzyme and catalog number. Classified as a standard formulation; verify recognition sequence, methylation sensitivity, temperature and recommended buffer. Confirm formulation, activity units and experimental conditions before substitution.

RM-04.013.376.002-0005-0R61611 pack optionManufacturer link
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SibEnzyme

XmaI

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XmaI restriction enzymes / Standard formulations

Same enzyme identity candidate. Verify recognition and cleavage specificity, methylation sensitivity, reaction buffer, concentration and heat inactivation in the source before substitution.

RM-04.013.377.001-0001-0See manufacturer1 pack optionManufacturer link
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Your selection checklist

  • 01Substrate specificity and intended application
  • 02Formulation, activity and concentration
  • 03Protocol conditions and required components
  • 04Pack size, storage and supplier documentation

ALTERNATIVE DOES NOT MEAN IDENTICAL

What to check before choosing a product

Final groups are designed around experimental substitution requirements. Group membership is provisional until the necessary technical details have been verified for the intended experiment.

Start with your application, then verify the technical requirements against each manufacturer’s documentation.

Explore manufacturer resources

Broader catalog resources for this branch. These links are discovery starting points, not verified replacements for individual products.