BIOLOGICAL DOMAIN
DNA engineering reagents support sequence-specific cutting, end modification, ligation, assembly and genome editing workflows.
Start with the change you want to make to DNA. Restriction digestion, ligation, assembly and end modification perform different steps, while genome editing introduces additional targeting requirements. Narrower categories distinguish enzyme identity, reaction role and formulation. A shared enzyme name alone does not establish matching cleavage behavior, buffer requirements or activity units.
Choose the required molecular activity before comparing substrate specificity, reaction conditions and supplied components.
Kinases, Phosphatases, Blunt-end preparation
48 productsDNA ligases, T4 DNA ligases, RNA ligases
77 productsProtelomerases, Helicases, Reverse gyrases
10 productsUracil excision, DNA repair enzymes, Base excision repair
32 productsCas9 reagents, Cas12 nucleases, Mutation detection
22 productsSite-specific recombinases, Recombination proteins
8 productsDNA polymerases, DNA polymerase fragments, Terminal transferases
27 productsDNA-degrading nucleases, Structure-specific nucleases, Exonucleases
113 productsSingle-stranded DNA binding
4 productsPCR cloning, Overlap assembly, Type IIS assembly
13 productsSite-directed mutagenesis
4 productsAatII restriction enzymes, Acc65I restriction enzymes, AccI restriction enzymes
942 productsDNA glucosylation
1 products
SphI restriction enzymes / Standard formulations
Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.
SphI restriction enzymes / High-fidelity formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
SphI restriction enzymes / High-fidelity formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
SphI restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
SphI restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
DNA ligases / SplintR Ligase
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
Cas9 reagents / SpRY Cas9 nucleases
Official manufacturer catalog lists this exact named enzyme and catalog code with a product-page hyperlink. Product-page body was unavailable due to a locale redirect; verify detailed conditions with the supplier. Confirm the supplier protocol, formulation and activity units before substitution.
SrFI restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
Sse8387I restriction enzymes / Standard formulations
Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.
SspI restriction enzymes / Fast-digest formulations
Same enzyme identity candidate. Verify recognition and cleavage specificity, methylation sensitivity, reaction buffer, concentration and heat inactivation in the source before substitution.
SspI restriction enzymes / Standard formulations
Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.
SspI restriction enzymes / Standard formulations
Exact named-enzyme comparison candidate. Use the supplier-specific buffer, incubation temperature, activity units and inactivation protocol. Review methylation sensitivity and star activity before substitution; this is not a validated drop-in replacement.
SspI restriction enzymes / Fast-digest formulations
Same enzyme identity candidate. Verify recognition and cleavage specificity, methylation sensitivity, reaction buffer, concentration and heat inactivation in the source before substitution.
SspI restriction enzymes / High-fidelity formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
SspI restriction enzymes / High-fidelity formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
StuI restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
StuI restriction enzymes / Standard formulations
Manufacturer catalog identifies the named restriction enzyme and catalog code. Isoschizomer aliases are not treated as interchangeable products; check cleavage position, methylation sensitivity, temperature and buffer. Confirm the supplier protocol, formulation and activity units before substitution.
StuI restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
StyD4I restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
StyI restriction enzymes / High-fidelity formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
Specialized DNA polymerases / Sulfolobus DNA polymerase IV
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
SwaI restriction enzymes / Standard formulations
Classification is based on the supplied product name. Confirm formulation, application and compatibility in the manufacturer documentation.
BamHI restriction enzymes / Fast-digest formulations
Manufacturer describes a SwiftCut restriction enzyme for rapid digestion in SwiftCut buffer. Verify recognition site, methylation sensitivity and digestion conditions. Confirm the supplier protocol, formulation and activity units before substitution.
BglII restriction enzymes / Fast-digest formulations
Manufacturer describes a SwiftCut restriction enzyme for rapid digestion in SwiftCut buffer. Verify recognition site, methylation sensitivity and digestion conditions. Confirm the supplier protocol, formulation and activity units before substitution.
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ALTERNATIVE DOES NOT MEAN IDENTICAL
Final groups are designed around experimental substitution requirements. Group membership is provisional until the necessary technical details have been verified for the intended experiment.
Start with your application, then verify the technical requirements against each manufacturer’s documentation.
Broader catalog resources for this branch. These links are discovery starting points, not verified replacements for individual products.